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Methods in Molecular Biology
cover

Bioinformatics for Cancer Immunotherapy

Methods and Protocols

Editors: Boegel, Sebastian (Ed.)

  • Includes cutting-edge methods and protocols
  • Provides step-by-step detail essential for reproducible results
  • Contains key notes and implementation advice from the experts
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  • ISBN 978-1-07-160327-7
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About this book

This volume focuses on a variety of in silico protocols of the latest bioinformatics tools and computational pipelines developed for neo-antigen identification and immune cell analysis from high-throughput sequencing data for cancer immunotherapy. The chapters in this book cover topics that discuss the two emerging concepts in recognition of tumor cells using endogenous T cells: cancer vaccines against neo-antigens presented on HLA class I and II alleles, and checkpoint inhibitors. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

Cutting-edge and authoritative, Bioinformatics for Cancer Immunotherapy: Methods and Protocols is a valuable research tool for any scientist and researcher interested in learning more about this exciting and developing field.


Table of contents (20 chapters)

Table of contents (20 chapters)
  • Bioinformatics for Cancer Immunotherapy

    Pages 1-9

    Holtsträter, Christoph (et al.)

  • An Individualized Approach for Somatic Variant Discovery

    Pages 11-36

    Li, Minghao (et al.)

  • Ensemble-Based Somatic Mutation Calling in Cancer Genomes

    Pages 37-46

    Huang, Weitai (et al.)

  • SomaticSeq: An Ensemble and Machine Learning Method to Detect Somatic Mutations

    Pages 47-70

    Fang, Li Tai

  • HLA Typing from RNA Sequencing and Applications to Cancer

    Pages 71-92

    Orenbuch, Rose (et al.)

Buy this book

eBook $169.00
price for USA in USD (gross)
  • ISBN 978-1-07-160327-7
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $219.99
price for USA in USD
  • ISBN 978-1-07-160326-0
  • Free shipping for individuals worldwide
  • Immediate ebook access, if available*, with your print order
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Bioinformatics for Cancer Immunotherapy
Book Subtitle
Methods and Protocols
Editors
  • Sebastian Boegel
Series Title
Methods in Molecular Biology
Series Volume
2120
Copyright
2020
Publisher
Springer US
Copyright Holder
Springer Science+Business Media, LLC, part of Springer Nature
eBook ISBN
978-1-07-160327-7
DOI
10.1007/978-1-0716-0327-7
Hardcover ISBN
978-1-07-160326-0
Series ISSN
1064-3745
Edition Number
1
Number of Pages
XII, 304
Number of Illustrations
9 b/w illustrations, 48 illustrations in colour
Topics

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