Happy Holidays—Our $30 Gift Card just for you, and books ship free! Shop now>>

Methods in Molecular Biology

Chimeric Antigen Receptor T Cells

Development and Production

Editors: Swiech, Kamilla, Malmegrim, Kelen Cristina Ribeiro, Picanço-Castro, Virgínia (Eds.)

Free Preview
  • Includes cutting-edge methods and protocols 
  • Provides step-by-step detail essential for reproducible results
  • Contains key notes and implementation advice from the experts
see more benefits

Buy this book

eBook n/a
  • ISBN 978-1-07-160146-4
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
Hardcover n/a
  • ISBN 978-1-07-160145-7
  • Free shipping for individuals worldwide
About this book

This volume provides comprehensive methods from expert scientists working in the  Chimeric Antigen Receptor T Cell (CAR-T Cell) field. Chapters guide readers through the state-of-art of CAR-T cell technology, CAR design and vector production, CAR-T cell generation and manufacturing, CAR-T cell characterization, and quality control. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

 Authoritative and cutting-edge, Chimeric Antigen Receptor T Cells: Development and Production aims to be useful in the production of CAR-T cells, especially for therapeutic purposes.

Table of contents (19 chapters)

Table of contents (19 chapters)
  • CAR-T Cells for Cancer Treatment: Current Design and Next Frontiers

    Pages 1-10

    Picanço-Castro, Virgínia (et al.)

  • Selection of Antibody Fragments for CAR-T Cell Therapy from Phage Display Libraries

    Pages 13-26

    Leyton-Castro, Nestor F. (et al.)

  • Phase I/II Manufacture of Lentiviral Vectors Under GMP in an Academic Setting

    Pages 27-60

    Dasgupta, Anindya (et al.)

  • Production of Lentivirus for the Establishment of CAR-T Cells

    Pages 61-67

    Lana, Marlous G. (et al.)

  • Optimized Production of Lentiviral Vectors for CAR-T Cell

    Pages 69-76

    Moço, Pablo Diego (et al.)

Buy this book

eBook n/a
  • ISBN 978-1-07-160146-4
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
Hardcover n/a
  • ISBN 978-1-07-160145-7
  • Free shipping for individuals worldwide
Loading...

Recommended for you

Loading...

Bibliographic Information

Bibliographic Information
Book Title
Chimeric Antigen Receptor T Cells
Book Subtitle
Development and Production
Editors
  • Kamilla Swiech
  • Kelen Cristina Ribeiro Malmegrim
  • Virgínia Picanço-Castro
Series Title
Methods in Molecular Biology
Series Volume
2086
Copyright
2020
Publisher
Springer US
Copyright Holder
Springer Science+Business Media, LLC, part of Springer Nature
eBook ISBN
978-1-07-160146-4
DOI
10.1007/978-1-0716-0146-4
Hardcover ISBN
978-1-07-160145-7
Series ISSN
1064-3745
Edition Number
1
Number of Pages
XI, 274
Number of Illustrations
4 b/w illustrations, 25 illustrations in colour
Topics