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Biology and Management of Lung Cancer

  • Book
  • © 1983

Overview

Editors:
  1. F. Anthony Greco

    1. Department of Medicine, Vanderbilt University Medical Center, Nashville, USA

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Part of the book series: Cancer Treatment and Research (CTAR, volume 11)

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Table of contents (11 chapters)

  1. Front Matter

    Pages i-xiv
    Download chapter PDF

  2. The In Vitro Growth and Characterization of Small Cell Lung Cancer

    • Desmond N. Carney, Adi F. Gazdar, Herbert K. Oie, Francis Cuttitta, John D. Minna
    Pages 1-24

  3. Monoclonal Antibodies Against Human Lung Cancer: Potential Diagnostic and Therapeutic Use

    • Frank Cuttitta, Steven Rosen, Desmond N. Carney, Adi F. Gazdar, John D. Minna
    Pages 25-36

  4. Transforming Growth Factors (TGFs) and Human Lung Cancer Cells

    • Stephen A. Sherwin, George J. Todaro
    Pages 37-49

  5. Tumor Cloning Assay: Application and Potential Usefulness in Lung Cancer Management

    • S. Kent Callahan, Charles A. Coltman Jr., Cliff Kitten, Daniel D. Von Hoff
    Pages 51-71

  6. Autologous Bone Marrow Transplantation — Potential Usefulness in Lung Cancer Management

    • Steven N. Wolff
    Pages 73-85

  7. Diagnosis of Poorly Differentiated Carcinoma of the Lung

    • John M. Lukeman, Bruce Mackay
    Pages 87-108

  8. Morphologic Changes in Small Cell Lung Cancer

    • Mehmet F. Fer, William W. Grosh, F. Anthony Greco
    Pages 109-124

  9. Lung Cancer Cachexia

    • Rowan T. Chlebowski, David Heber, Jerome B. Block
    Pages 125-142

  10. The Neurophysins and Small Cell Lung Cancer

    • William G. North, L. Herbert Maurer, Joseph F. O’Donnell
    Pages 143-169

  11. The Potential Role of Surgery in the Contemporary Combined Modality Management of Small Cell Anaplastic Lung Cancer

    • Robert L. Comis
    Pages 171-189

  12. Chemotherapy and Radiation Therapy of Non-Small Cell Lung Carcinoma

    • Kenneth R. Hande, Arnold W. Malcolm
    Pages 191-217

  13. Back Matter

    Pages 219-222
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Keywords

About this book

Lung cancer remains an extremely difficult neoplasm to treat effectively. A large part of our lack of success in dealing with these patients is related to our empiric therapeutic attempts. Slowly our basic understanding of the lung cancers is improving and techniques are becoming available to allow us to better understand the biology of these neoplasms. This volume reviews several areas of interest in regard to the biologic behavior and characteris­ of lung cancer. tics Chapters deal with the in vitro growth of small cell lung cancer, the inves­ tigation of growth factors in human lung cancer, the production of mono­ clonal antibodies against lung cancer and the application and potential use­ fulness of the human tumor cloning assay in lung cancer management. These avenues of investigation are likely to establish a more scientific basis on which more rational therapy can be designed. Carney and associates have established several continuous small cell lung cancer cell lines in their laboratory. The amine precursor uptake and decar­ boxylation (APUD) properties of this neoplasm have been confirmed by demonstrating the presence of neurosecretory granules and high levels of the APUD enzyme L-dopa decarboxylase. In addition, several new markers have been documented including bombesin, creatine-kinase BB and neuron­ specific enolase. These tumor products along with others may be useful serum markers in patients with small cell lung cancer.

Editors and Affiliations

  • Department of Medicine, Vanderbilt University Medical Center, Nashville, USA

    F. Anthony Greco

Bibliographic Information

  • Book Title: Biology and Management of Lung Cancer

  • Editors: F. Anthony Greco

  • Series Title: Cancer Treatment and Research

  • DOI: https://doi.org/10.1007/978-1-4613-3849-9

  • Publisher: Springer New York, NY

  • eBook Packages: Springer Book Archive

  • Copyright Information: Martinus Nijhoff Publishers, Boston 1983

  • Hardcover ISBN: 978-0-89838-554-0Published: 31 March 1983

  • Softcover ISBN: 978-1-4613-3851-2Published: 12 October 2011

  • eBook ISBN: 978-1-4613-3849-9Published: 06 December 2012

  • Series ISSN: 0927-3042

  • Series E-ISSN: 2509-8497

  • Edition Number: 1

  • Number of Pages: XIV, 222

  • Topics: Oncology

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