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Developments in Oncology

Breast Cancer: Scientific and Clinical Progress

Proceedings of the Biennial Conference for the International Association of Breast Cancer Research, Miami, Florida, USA — March 1–5, 1987

Editors: Rich, Marvin A., Hager, Jean Carol, Lopez, Diana M. (Eds.)

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  • ISBN 978-1-4613-1753-1
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About this book

Effective control of breast cancer depends on three types of research accomplishment -- understanding the disease's origins and progression: successfully applying this knowledge to methods of detection, diagnosis and treatment: and finding ways to make these advances truly available to the public as effectively as possible. The significant progress that is occurring across this entire spectrum of pioneering investigation is reflected in these proceedings of the 1987 biennial conference of the International Association for Breast Cancer Research. The first section of the book focuses on oncogenes and chemical effectors that may play key roles in early cell transformation leading to breast cancer. Research discussed includes identification of specific oncogenes which appear to be involved in the disease, study of their activation and expression, examination of the biological effects of various growth factors isolated from breast cancer cell lines, and investigation of the molecular mechanisms by which estrogens promote and stimulate growth of breast cancers. The second group of chapters deals with several other complex factors and phenomena which may influence tumor formation in the breast, for example, expression of abnormalities by fibroblasts, disruption of epithelial-mesenchymal interactions, and loss of ability nili to synthesize normal basal lamina resulting in alterations in the extracellular matrix. Clarification of the processes of normal mammary gland development and differentiation is central to much of this work.

Table of contents (25 chapters)

Table of contents (25 chapters)
  • An Analysis of Three Proto-Oncogenes in Primary Human Breast Tumor DNAs: The c-mos, the c-erbB-2 and the Epidermal Growth Factor Receptor Genes

    Pages 1-10

    Hynes, N. E. (et al.)

  • Proviral Activation of Potential Oncogenes in Tumors Induced by Mouse Mammary Tumor Virus

    Pages 11-23

    Peters, Gordon (et al.)

  • Quantitative and Qualitative Changes in Oncogene Expression During Carcinogenesis

    Pages 24-41

    Spandidos, D. A. (et al.)

  • Mammary Tumor-Associated Growth Factors Origins and Possible Functions

    Pages 42-54

    Kidwell, W. R. (et al.)

  • The Oestrogen-Induced pS2 Gene and the Oestrogen Receptor in Breast Cancer

    Pages 55-67

    Chambon, P. (et al.)

Buy this book

eBook $169.00
price for USA in USD
  • ISBN 978-1-4613-1753-1
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $279.99
price for USA in USD
Softcover $219.99
price for USA in USD
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Bibliographic Information

Bibliographic Information
Book Title
Breast Cancer: Scientific and Clinical Progress
Book Subtitle
Proceedings of the Biennial Conference for the International Association of Breast Cancer Research, Miami, Florida, USA — March 1–5, 1987
Editors
  • Marvin A. Rich
  • Jean Carol Hager
  • Diana M. Lopez
Series Title
Developments in Oncology
Series Volume
56
Copyright
1988
Publisher
Springer US
Copyright Holder
Kluwer Academic Publishers, Boston
eBook ISBN
978-1-4613-1753-1
DOI
10.1007/978-1-4613-1753-1
Hardcover ISBN
978-0-89838-387-4
Softcover ISBN
978-1-4612-8984-5
Edition Number
1
Number of Pages
XIX, 389
Topics

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