Methods in Molecular Biology

Recombinant Antibodies for Cancer Therapy

Methods and Protocols

Editors: Welschof, Martin, Krauss, Jürgen (Eds.)

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eBook $169.00
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  • ISBN 978-1-59259-334-7
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Hardcover $219.99
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  • ISBN 978-0-89603-918-6
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Softcover $219.99
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  • ISBN 978-1-61737-250-6
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About this book

Many antibodies recently developed as therapeutic agents have been tailored by the powerful new recombinant antibody technology, and already their clinical data show highly encouraging results. In Recombinant Antibodies for Cancer Therapy: Methods and Protocols, Martin Welschof and Jürgen Krauss present a collection of carefully selected protocols for the design, construction, and characterization of those novel anticancer therapeutics. Written by seasoned investigators who have successfully verified the particular method described, these readily reproducible methods include coverage of hybridoma-derived recombinant antibodies, recombinant antibody fragments from phagemid-displayed antibody repertoires, antibody fragments with additional properties, and large-scale production of recombinant antibodies for clinical applications. The main focus is on providing detailed protocols that describe these procedures step-by-step, accompanied by a troubleshooting guide discussing possible problems and offering many tips for their potential solutions. Concise review articles also survey the current status of recombinant antibodies in cancer therapy, as well as the generation of antibody molecules through antibody engineering.
Up-to-date and highly practical, Recombinant Antibodies for Cancer Therapy: Methods and Protocols surveys the current status of engineered antibodies and describes in rich detail many readily reproducible methods of generating the novel and promising antibody-based reagents of today's cancer therapy.

Reviews

"...the book is well written and the experimental protocols that were included are described in great detail...this book is a valuable resource both for persons new to this field to get an overview of current activities and for those already in the field to look up specific areas that are covered." -Clinical Immunology

"Overall the book is a helpful resource, especially for molecular biologists involved in generating antibody fragments, collecting up to date protocols in one convenient volume." - Pharmaceutical Research

Table of contents (28 chapters)

Table of contents (28 chapters)

Buy this book

eBook $169.00
price for USA in USD (gross)
  • ISBN 978-1-59259-334-7
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $219.99
price for USA in USD
  • ISBN 978-0-89603-918-6
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $219.99
price for USA in USD
  • ISBN 978-1-61737-250-6
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Recombinant Antibodies for Cancer Therapy
Book Subtitle
Methods and Protocols
Editors
  • Martin Welschof
  • Jürgen Krauss
Series Title
Methods in Molecular Biology
Series Volume
207
Copyright
2003
Publisher
Humana Press
Copyright Holder
Humana Press
eBook ISBN
978-1-59259-334-7
DOI
10.1385/1592593348
Hardcover ISBN
978-0-89603-918-6
Softcover ISBN
978-1-61737-250-6
Series ISSN
1064-3745
Edition Number
1
Number of Pages
XIV, 481
Topics