Cytokines and Autoimmune Diseases

Editors: Kuchroo, V.K., Sarvetnick, N., Hafler, D.A., Nicholson, L.B. (Eds.)

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About this book

Although the role of cytokines and chemokines in the induction and regulation of autoimmunity has a vast current literature, there is as yet no clear consensus about the details of this complex process. In Cytokines and Autoimmune Diseases, leading researchers synthesize the available information to help develop an intimate understanding of how cytokines and chemokines are involved in the pathogenesis of autoimmune diseases. The many chapters offer critical reviews of the basic mechanisms controlling cytokine induction and regulation, as well as the resulting production of proinflammatory and anti-inflammatory cytokines, the former of which induces organ-specific autoimmune diseases. From the vantage of these insights, they address the role of cytokines in a wide variety of autoimmune disease, uvetis, encephalomyelitis, multiple sclerosis, human type 1 diabetes, rheumatoid arthritis, SLE, and myasthenia gravis.
Authoritative and state-of-the-art, Cytokines and Autoimmune Diseases comprehensively integrates the diffuse literature of this dramatically advancing field, and highlights the enormous therapeutic potential of cytokine modulation in the treatment of autoimmune disease.

Reviews

"Authoritative and state-of-the-art, Cytokines and Autoimmune Disease highlights the enormous therapeutic potential of cytokine modulation in the treatment of autoimmune disease." -Immunology News

Table of contents (16 chapters)

Table of contents (16 chapters)
  • Transcriptional Regulation of Cytokine Gene Expression in Th Subsets

    Pages 3-23

    Rengarajan, Jyothi (et al.)

  • Chromatin Remodeling and Transcriptional Regulation of Cytokine Gene Expression in T Cells

    Pages 25-48

    Shannon, M. Frances (et al.)

  • Variant Ligands, Altered T Cell Receptor Signaling, Hierarchical Response Thresholds, and CD4

    Pages 49-78

    Itoh, Yasushi (et al.)

  • The Role of Costimulation in T Cell Differentiation

    Pages 79-118

    Buhlmann, Janet E. (et al.)

  • CD1d-Restricted NK T Cells and Autoimmunity

    Pages 119-141

    Exley, Mark (et al.)

Buy this book

eBook $149.00
price for USA in USD
  • ISBN 978-1-59259-129-9
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $199.99
price for USA in USD
  • ISBN 978-0-89603-856-1
  • Free shipping for individuals worldwide
  • Institutional customers should get in touch with their account manager
  • Covid-19 shipping restrictions
  • Usually ready to be dispatched within 3 to 5 business days, if in stock
Softcover $199.99
price for USA in USD
  • ISBN 978-1-61737-225-4
  • Free shipping for individuals worldwide
  • Institutional customers should get in touch with their account manager
  • Covid-19 shipping restrictions
  • Usually ready to be dispatched within 3 to 5 business days, if in stock
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Bibliographic Information

Bibliographic Information
Book Title
Cytokines and Autoimmune Diseases
Editors
  • Vijay K. Kuchroo
  • Nora Sarvetnick
  • David A. Hafler
  • Lindsay B. Nicholson
Copyright
2002
Publisher
Humana Press
Copyright Holder
Springer Science+Business Media New York
eBook ISBN
978-1-59259-129-9
DOI
10.1007/978-1-59259-129-9
Hardcover ISBN
978-0-89603-856-1
Softcover ISBN
978-1-61737-225-4
Edition Number
1
Number of Pages
XI, 422
Number of Illustrations
23 b/w illustrations
Topics