Cancer Drug Discovery and Development

Matrix Metalloproteinase Inhibitors in Cancer Therapy

Editors: Clendeninn, Neil J., Appelt, Krzysztof (Eds.)

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  • ISBN 978-1-59259-011-7
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Hardcover $219.99
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Softcover $219.99
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  • ISBN 978-1-61737-123-3
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About this book

The association of matrix metalloproteinases (MMPs)-enzymes that disrupt the body's normal repair functions-with several diseases, including growing and invasive tumors, holds the tantalizing promise that their inhibiton might have therapeutic value. In Matrix Metalloproteinase Inhibitors in Cancer Therapy, cutting-edge investigators review the current status of the entire field, from the biology of MMPs through the current clinical studies. The authors include many leading scientists from pharmaceutical companies who present all the latest concepts and results on the preferred design strategies for MMP inhibitors, their molecular mechanisms, and their substrates. In addition, they fully describe their company's research effort on specific MMP inhibitors, detailing vanguard design strategies, their in vitro activity, the outcome of animal model studies and, where available, their toxicology, safety, and efficacy in human clinical trials. Comprehensive and state-of-the-art, Matrix Metalloproteinase Inhibitors offers basic and clinical investigators alike a richly informative summary of all the latest research on these powerful new drugs, and their high promise as emerging cancer therapeutics.

Table of contents (10 chapters)

Table of contents (10 chapters)

Buy this book

eBook $169.00
price for USA in USD (gross)
  • ISBN 978-1-59259-011-7
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $219.99
price for USA in USD
  • ISBN 978-0-89603-668-0
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $219.99
price for USA in USD
  • ISBN 978-1-61737-123-3
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Matrix Metalloproteinase Inhibitors in Cancer Therapy
Editors
  • Neil J. Clendeninn
  • Krzysztof Appelt
Series Title
Cancer Drug Discovery and Development
Copyright
2001
Publisher
Humana Press
Copyright Holder
Springer Science+Business Media New York
eBook ISBN
978-1-59259-011-7
DOI
10.1007/978-1-59259-011-7
Hardcover ISBN
978-0-89603-668-0
Softcover ISBN
978-1-61737-123-3
Series ISSN
2196-9906
Edition Number
1
Number of Pages
XIII, 262
Number of Illustrations
26 b/w illustrations, 3 illustrations in colour
Topics