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Autoimmune Reactions

  • Book
  • © 1999

Overview

Editors:
  1. Sudhir Paul

    1. Department of Pathology and Laboratory Medicine, Health Sciences Center, University of Texas Medical School, Houston, USA

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Part of the book series: Contemporary Immunology (CONTIM)

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Table of contents (25 chapters)

  1. Front Matter

    Pages i-xiv
    Download chapter PDF

  2. Diversity of Immunological Defects in Autoimmune Diseases

    • Sudhir Paul
    Pages 1-4

  3. Insights into Mechanisms of Autoimmune Disease Based on Clinical Findings

    • Noel R. Rose
    Pages 5-17

  4. Autoimmunity and B-Cell Malignancies

    • Otto Pritsch, Guillaume Dighiero
    Pages 19-30

  5. Pathogenesis of Autoimmune Thyroid Disease

    • Ramzi A. Ajjan, Anthony P. Weetman
    Pages 31-59

  6. Autoantigens of Sjögren’s Syndrome

    • Isao Nishimori, Michael A. Hollingsworth
    Pages 61-77

  7. Autoimmunity in Patients with Essential Hypertension

    • Israel Rubinstein
    Pages 79-83

  8. Autoimmune Antigen Presentation Mechanisms

    • Edward Dwyer
    Pages 85-97

  9. Induction of Pathogenic Autoimmune T-Cell and Autoantibody Responses Through T-Cell Epitope Mimicry

    • Kenneth S. K. Tung, Kristine M. Garza, Ya-huan Lou
    Pages 99-112

  10. T-Cell Antigen Receptor Repertoire in Rheumatoid Arthritis

    • James W. Edinger, David N. Posnett
    Pages 113-140

  11. The Role of Exogenous Stimulation in Pathogenesis of Autoimmune Diseases

    • Constantin Bona, Chihiro Murai, Takeshi Sasaki
    Pages 141-155

  12. Dysregulation of the Idiotype Network in Autoimmune Diseases

    • Haraldine A. Stafford, Morris Reichlin
    Pages 157-176

  13. The Role of Variable Region Gene Rearrangements in the Generation of Autoantibodies

    • Anne Davidson
    Pages 177-190

  14. Autoantibodies Against Ig Immunoglobulin Framework Epitopes

    • Heinz Kohler, Sybille Müller
    Pages 191-199

  15. Autoantibodies to T-Cell Receptors

    • John J. Marchalonis, Samuel F. Schluter, David E. Yocum
    Pages 201-219

  16. Autoantibody Catalysis

    • Sudhir Paul
    Pages 221-234

  17. Is the Catalytic Activity of Bence Jones Proteins an Autoimmune Effector Mechanism in Multiple Myeloma?

    • Hyogo Sinohara, Kinji Matsuura
    Pages 235-247

  18. Kidney Damage in Autoimmune Disease

    • Gerald C. Groggel
    Pages 249-268

  19. DNA as Immunogen for the Induction of Immune and Autoimmune Antibody in Mice

    • Tony N. Marion
    Pages 269-292

  20. Cellular Entry and Nuclear Localization of Anti-DNA Antibodies

    • Kumiko Yanase, Michael P. Madaio
    Pages 293-304
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Keywords

About this book

Autoimmune Reactions tackles fundamental questions about how the immune system can destroy invading microbial pathogens without causing damage to itself and other "self" systems. The authoritative experts writing here explore the mechanistic aspects of such autoimmune diseases as lupus, rheumatoid arthritis, diabetes, and autoimmune thyroid disease, and where possible delineate how malfunctioning immunological mechanisms can lead to clinical symptoms. They also discusses possible general mechanisms of autoimmune disease-e.g., molecular mimicry and dysfunctional antigen presentation-and their current limitations as unifying explanations of the diseases described. The book illustrates the type of thinking and research that should eventually permit development of palliatives and cures for autoimmune diseases.

Reviews

"...tackles fundamental questions about how the immune system can destroy invading microbial pathogens without causing damage to itself and other "self" systems.The authoritative expert writers explore the mechanistic aspects of...autoimmune diseases...and where possible, delineate how malfunctioning immunological mechanisms can lead to clinical symptoms. They also discuss possible general mechanisms of autoimmune disease...and their current limitations as unifying explanations of the disease described. The book illustrates the type of thinking and research that should eventually permit development of palliatives and cures for autoimmune diseases."-Journal of Investigational Allergology and Clinical Immunology

Editors and Affiliations

  • Department of Pathology and Laboratory Medicine, Health Sciences Center, University of Texas Medical School, Houston, USA

    Sudhir Paul

Bibliographic Information

  • Book Title: Autoimmune Reactions

  • Editors: Sudhir Paul

  • Series Title: Contemporary Immunology

  • DOI: https://doi.org/10.1007/978-1-4612-1610-0

  • Publisher: Humana Totowa, NJ

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer Science+Business Media New York 1999

  • Hardcover ISBN: 978-0-89603-550-8Published: 08 October 1998

  • Softcover ISBN: 978-1-4612-7215-1Published: 10 October 2012

  • eBook ISBN: 978-1-4612-1610-0Published: 06 December 2012

  • Edition Number: 1

  • Number of Pages: XIV, 438

  • Topics: Immunology

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