Contemporary Neuroscience

Molecular Mechanisms of Dementia

Editors: Wasco, Wilma, Tanzi, Rudolph (Eds.)

Free Preview

Buy this book

eBook $129.00
price for USA in USD (gross)
  • ISBN 978-1-59259-471-9
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $219.99
price for USA in USD
  • ISBN 978-0-89603-371-9
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $169.99
price for USA in USD
  • ISBN 978-1-4757-5889-4
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

Wilma Wasco and Rudolph Tanzi bring together in Molecular Mechanisms of Dementia the best and latest thinking by leading scientists on the etiologic and pathogenic events responsible for the onset of Alzheimer's disease and related dementias. In presenting the various mechanisms and multifaceted approaches currently being employed, the distinguished contributors review such critical factors as apoptosis, energy metabolism, excitotoxicity and calcium-mediated cell death, free radicals, electrophysiological abnormalities, environmental toxins, degeneration of neural networks, and modification of the cytoskeleton. They also examine mechanisms by which ischemia and hypoxia result in dementia.

Molecular Mechanisms of Dementia is the first major contemporary review of this dramatically advancing field. It provides an invaluable summary of the tremendous progress that has been made in developing testable models of the molecular mechanisms of dementia, as well as critical insights into the necessary direction of future investigations of dementia. The book is certain to become a standard reference for all researchers now working in the field of neurodegenerative disorders.

Reviews

In conclusion, the first chapters of this book provide a lot of very recent information related to the production and the toxicity of the amyloid peptide as well as to the possible role of new genes involved in Alzheimer's disease. It represents a very interesting review for scientists studying the cellular and molecular mechanisms involved in the neurodegeneration of Alzheimer's disease.-ACTA Neurologica Belgica

"The text is logically organized, which helps in making a transition from one subject to the other. The topics are well selected; classical, and new, often controversial, research is covered. Each chapter is succinct and ends with an informative summary...this expertly written overview also provides directions for future studies...a valuable reference and source of inspiration. It is highly recommended to all interested in the molecular basis of neurodegenerative diseases."-Cell Biology International

Table of contents (18 chapters)

Table of contents (18 chapters)
  • Etiological Clues from Gene Defects Causing Early Onset Familial Alzheimer’s Disease

    Wasco, Wilma (et al.)

    Pages 1-19

  • Potential Biological Mechanisms of ApoE in Alzheimer’s Disease

    Rebeck, G. William

    Pages 21-37

  • Understanding the Biology and Molecular Pathogenesis of Alzheimer’s Disease in Transgenic Mice Expressing Amyloid Precursor Proteins

    Hsiao, Karen K.

    Pages 39-43

  • Mechanism for β-amyloid Overproduction in Alzheimer Disease

    Volloch, Vladimir

    Pages 45-56

  • Apoptosis and Alzheimer’s Disease

    LeBlanc, Andréa

    Pages 57-71

Buy this book

eBook $129.00
price for USA in USD (gross)
  • ISBN 978-1-59259-471-9
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $219.99
price for USA in USD
  • ISBN 978-0-89603-371-9
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $169.99
price for USA in USD
  • ISBN 978-1-4757-5889-4
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Loading...

Services for this Book

Recommended for you

Loading...

Bibliographic Information

Bibliographic Information
Book Title
Molecular Mechanisms of Dementia
Editors
  • Wilma Wasco
  • Rudolph Tanzi
Series Title
Contemporary Neuroscience
Copyright
1997
Publisher
Humana Press
Copyright Holder
Springer Science+Business Media New York
eBook ISBN
978-1-59259-471-9
DOI
10.1007/978-1-59259-471-9
Hardcover ISBN
978-0-89603-371-9
Softcover ISBN
978-1-4757-5889-4
Edition Number
1
Number of Pages
XI, 312
Number of Illustrations
33 b/w illustrations, 2 illustrations in colour
Topics