Neuromethods

Neurotrophic Factors

Editors: Boulton, Alan A., Baker, Glen B., Hefti, Franz (Eds.)

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About this book

The field of neurotrophic factors has witnessed exp- sive growth in the past decade. As is usual in scientific in- vation, this progress has been closely associated with methodological advances. The introduction of molecular b- logical techniques into the neurotrophic factor field led to the discovery of new families of neurotrophic growth f- tors and their receptors. Production of growth factors by recombinant technology played a crucial part. The example of nerve growth factor, the paradigmatic neurotrophic factor, illustrates this point. A decade ago investigators were forced to purify small quantities of this protein from murine salivary glands, but much larger qu- tities of recombinant nerve growth factor are now available for experimentation as well as clinical development. A decade ago there was a controversy about the existence of nerve growth factor in the brain and the immunoassays used for its measurement, but current publications report the precise localization of gene expression for nerve growth factor and its receptor in the brain. Neurotrophic Factors aims at presenting the techniques that have been crucial to the realization of these rapid advances and thus have helped propel the neurotrophic factors field to its current status of high visibility. These techniques range from molecular biological methods used for cloning and production, to cell culture methods for assessing biological activities, to animal models of nervous system injury (nec- sary for the development of therapeutic agents from neurotrophic factors).

Reviews

...strength of the book lies in the comprehensive methodology...a welcome addition to any neurobiologist's library. - Journal of Neurochemistry

Table of contents (12 chapters)

Table of contents (12 chapters)

Buy this book

eBook $119.00
price for USA in USD
  • ISBN 978-1-59259-630-0
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $219.99
price for USA in USD
  • ISBN 978-0-89603-249-1
  • Free shipping for individuals worldwide
  • Institutional customers should get in touch with their account manager
  • Covid-19 shipping restrictions
  • Usually ready to be dispatched within 3 to 5 business days, if in stock
Softcover $159.99
price for USA in USD
  • ISBN 978-1-4899-3987-6
  • Free shipping for individuals worldwide
  • Institutional customers should get in touch with their account manager
  • Covid-19 shipping restrictions
  • Usually ready to be dispatched within 3 to 5 business days, if in stock
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Bibliographic Information

Bibliographic Information
Book Title
Neurotrophic Factors
Editors
  • Alan A. Boulton
  • Glen B. Baker
  • Franz Hefti
Series Title
Neuromethods
Series Volume
25
Copyright
1993
Publisher
Humana Press
Copyright Holder
Springer Science+Business Media New York
eBook ISBN
978-1-59259-630-0
DOI
10.1385/0896032493
Hardcover ISBN
978-0-89603-249-1
Softcover ISBN
978-1-4899-3987-6
Series ISSN
0893-2336
Edition Number
1
Number of Pages
XVIII, 422
Topics