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Experimental Biology and Medicine

International Symposium: Retroviruses and Human Pathology

Authors: Gallo, Robert C., Stehelin, Dominique, Varnier, Oliviero E.

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Hardcover $279.00
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About this book

For decades retroviruses have been riding the crest of a wave of experimental research directed toward the identification of an infectious agent of human neoplastic diseases. In the early 1970s, several scientists successfully demonstrated the presence of retroviruses in numerous animal species and proved their etiological role in some related diseases. Corresponding findings in humans were somewhat discouraging. Although financial support for this line· of research declined, a few dedicated retrovirologists survived and continued to collect more biological information and technological expertise that opened a new approach to the search for a human retrovirus. The rewards came with the discovery that the genes responsible for neoplastic transformation (oncogenes) are of cellular origin and can be shuttled about by retroviruses, and with the identification of a new family of Human T-cell Lymphotrophic retroViruses (HTLV) from patients with diseases ranging from leukemia to the acquired immunodeficiency syndrome (AIDS). An understanding of the role and significance of retroviruses in human pathology requires basic knowledge of the major animal systems studied. With this perspective in mind, we present here a survey that includes general overviews, minireviews on each animal system studied with selected experimental reports and, finally, a stimulating review of the field of human retrovirology by many of the pioneer scientists who created it. We are especially grateful to Profs. C. A. Romanzi and G. C. Schito for promoting the organization of the Symposium. On behalf of the Sym­ posium Committee, we thank E. Soeri, L. Casarino, G. P. Gesu, M.

Table of contents (43 chapters)

  • Opening Remarks

    Romanzi, Carmine A.

    Pages 1-1

  • Retroviruses in Neoplasia Yesterday, Today and Tomorrow

    Oker-Blom, N. (et al.)

    Pages 3-17

  • The Role of Retroviruses in Nature

    Dulbecco, R.

    Pages 19-33

  • Changing Dogmas in Retrovirology

    Levy, J. A.

    Pages 35-59

  • The Biology of Endogenous Leukemia Viruses: A Study of the DBA/2 Mouse

    Nexø, B. A.

    Pages 63-76

Buy this book

eBook $169.00
price for USA in USD (gross)
  • ISBN 978-1-4612-5008-1
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $279.00
price for USA in USD
  • ISBN 978-0-89603-098-5
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $219.00
price for USA in USD
  • ISBN 978-1-4612-9396-5
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
International Symposium: Retroviruses and Human Pathology
Authors
Series Title
Experimental Biology and Medicine
Series Volume
11
Copyright
1985
Publisher
Humana Press
Copyright Holder
The Humana Press Inc.
eBook ISBN
978-1-4612-5008-1
DOI
10.1007/978-1-4612-5008-1
Hardcover ISBN
978-0-89603-098-5
Softcover ISBN
978-1-4612-9396-5
Edition Number
1
Number of Pages
XXIV, 557
Topics