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Contemporary Biomedicine

Human Cancer Markers

Editors: Sell, Stewart, Wahren, Britta (Eds.)

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About this book

The ability to diagnose cancer by simple measurement of a serum or tissue' 'marker" has been a goal of medical science for many years. There is ample evidence that tumor cells are different from normal cells and pro­ duce substances that can be detected by currently available immuno­ chemical or biochemical methods. These "cancer markers" may be se­ creted proteins, enzymes, hormones, fetal serum components, monoclonal immunoglobulins, cell surface components, or cytoplasmic constituents. The purpose of this book is to present the current status of our knowledge of such cancer markers. The first tumor marker identified by laboratory means was Bence­ Jones protein. In a series of lectures delivered to the Royal College of Phy­ sicians in London in 1846, Dr. H. Bence Jones described studies on a urine sample sent to him with the following note: "Dear Dr. Jones-The tube contains urine of very high specific gravity. When boiled it becomes slightly opaque . . . . etc. " Dr. Jones found that heating of the urine after addition of nitric acid resulted in formation of a heavy precipitate; acid ad­ dition may have been required to bring the urine to pH 4-6 at which Bence Jones proteins are more likely to precipitate when heated. This urinary pre­ cipitate was associated with a bone disease termed "mollities ossium. " [H. Bence Jones, Papers on Chemical Pathology, Lecture III. Lancet 2, 269-274 (1847)].

Table of contents (16 chapters)

Table of contents (16 chapters)

Buy this book

eBook $109.00
price for USA in USD
  • ISBN 978-1-4612-5808-7
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $159.99
price for USA in USD
  • ISBN 978-0-89603-029-9
  • Free shipping for individuals worldwide
  • Immediate ebook access, if available*, with your print order
  • Usually dispatched within 3 to 5 business days.
Softcover $139.99
price for USA in USD
  • ISBN 978-1-4612-5810-0
  • Free shipping for individuals worldwide
  • Immediate ebook access, if available*, with your print order
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Human Cancer Markers
Editors
  • Stewart Sell
  • Britta Wahren
Series Title
Contemporary Biomedicine
Series Volume
2
Copyright
1982
Publisher
Humana Press
Copyright Holder
HUMANA Press Inc.
eBook ISBN
978-1-4612-5808-7
DOI
10.1007/978-1-4612-5808-7
Hardcover ISBN
978-0-89603-029-9
Softcover ISBN
978-1-4612-5810-0
Edition Number
1
Number of Pages
XX, 428
Topics

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