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Diagnostic and Therapeutic Advances in Pediatric Oncology

  • Book
  • © 1997

Overview

Editors:
  1. David O. Walterhouse

    1. Robert H. Lurie Cancer Center, Northwestern University Medical School, Chicago, USA
      Department of Pediatrics, Children’s Memorial Hospital, Chicago, USA

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  2. Susan L. Cohn

    1. Robert H. Lurie Cancer Center, Northwestern University Medical School, Chicago, USA
      Department of Pediatrics, Children’s Memorial Hospital, Chicago, USA

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Part of the book series: Cancer Treatment and Research (CTAR, volume 92)

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Table of contents (11 chapters)

  1. Front Matter

    Pages i-xi
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  2. Understanding the Causes of Tumors of Childhood

    1. Front Matter

      Pages 1-1
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    2. Embryonic development and pediatric oncogenesis

      • David O. Walterhouse, Joon Won Yoon
      Pages 3-38

    3. Immunodeficiency states and related malignancies

      • Kenneth L. McClain
      Pages 39-61

    4. Familial cancer syndromes and genetic counseling

      • Gail E. Tomlinson
      Pages 63-97

  3. Embryonal Tumors

    1. Front Matter

      Pages 99-99
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    2. Molecular basis of Wilms’ tumor

      • Paul Grundy
      Pages 101-123

    3. Neuroblastoma: solving a biologic puzzle

      • Susan L. Cohn, Dafna Meitar, Morris Kletzel
      Pages 125-162

    4. Pediatric germ cell tumors

      • Elizabeth J. Perlman, Cynthia Kretschmar
      Pages 163-200

    5. Hepatic malignancies in childhood and adolescence (hepatoblastoma, hepatocellular carcinoma, and embryonal sarcoma)

      • Edwin C. Douglass
      Pages 201-212

  4. Sarcomas

    1. Front Matter

      Pages 213-213
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    2. Osteosarcoma

      • Jeffrey S. Dome, Cindy L. Schwartz
      Pages 215-251

    3. The Ewing’s sarcoma family of tumors: Ewing’s sarcoma and peripheral primitive neuroectodermal tumor of bone and soft tissue

      • Linda Granowetter, Daniel C. West
      Pages 253-308

    4. Rhabdomyosarcoma: biology and therapy

      • Alberto S. Pappo, David N. Shapiro
      Pages 309-339

  5. Late Effects of Childhood Cancer

    1. Front Matter

      Pages 341-341
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    2. Late effects of cancer therapy

      • Elaine R. Morgan, Maureen Haugen
      Pages 343-375

  6. Back Matter

    Pages 377-387
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Keywords

About this book

The purpose of Diagnostic and Therapeutic Advances in Pediatric Oncology for the Cancer Treatment and Research Series is to provide an up-to-date summary of how recent advances in cancer research are being applied to the care of children with solid tumors. The interface of cancer research with clinical practice in pediatric oncology has never been more intimate than today. While researchers are identifying oncogenes and tumor suppressor genes and are studying their specific functions, clinicians are using knowledge of oncogenes and tumor suppressor genes for diagnosing cancer in children, for therapeutic decision-making purposes, and for prognostic purposes. The first three chapters in this book describe models for understanding the causes of childhood cancer that were perhaps initially identified by clinicians and that are now being studied and understood by researchers. These chapters will describe research evidence that supports roles for the involvement of normal developmental regulatory genes in childhood oncogenesis, of abnormal immune regulation in childhood oncogenesis, and of heredity in childhood oncogenesis. The next eight chapters are devoted to descriptions of the appli­ cation of new research developments to clinical practice with reference to the most common forms of solid tumors of childhood outside the central nervous system. The final chapter will describe late effects of childhood cancer and its therapy and the impact research is having on understanding and perhaps preventing these late effects.

Editors and Affiliations

  • Robert H. Lurie Cancer Center, Northwestern University Medical School, Chicago, USA

    David O. Walterhouse, Susan L. Cohn

  • Department of Pediatrics, Children’s Memorial Hospital, Chicago, USA

    David O. Walterhouse, Susan L. Cohn

Bibliographic Information

  • Book Title: Diagnostic and Therapeutic Advances in Pediatric Oncology

  • Editors: David O. Walterhouse, Susan L. Cohn

  • Series Title: Cancer Treatment and Research

  • DOI: https://doi.org/10.1007/978-1-4615-5767-8

  • Publisher: Springer New York, NY

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer Science+Business Media New York 1997

  • Hardcover ISBN: 978-0-7923-9978-0Published: 31 January 1998

  • Softcover ISBN: 978-1-4613-7643-9Published: 10 October 2012

  • eBook ISBN: 978-1-4615-5767-8Published: 06 December 2012

  • Series ISSN: 0927-3042

  • Series E-ISSN: 2509-8497

  • Edition Number: 1

  • Number of Pages: XI, 387

  • Topics: Oncology, Cancer Research

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