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Table of contents (22 chapters)
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Front Matter
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Growth hormone secretion and mechanisms of action
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Front Matter
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Growth hormone replacement therapy in adult GH deficient patients
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Front Matter
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Keywords
About this book
Shlomo Melmed, MD, Series Editor, Endocrine Updates
Ten years ago, many endocrinologists were still skeptical that growth hormone (GH) played an active role in adult metabolism. This is, perhaps, surprising given that GH deficiency (GHD) in adulthood had been `recognized' as long ago as the 1960s.
During the last ten years studies have shown that GHD in adulthood is a far-reaching syndrome associated with abnormal body composition, reduced bone mineral density with an increased fracture rate, increased cardiovascular morbidity and impaired cardiac function, as well as reduced exercise performance and decreased psychological well-being. Importantly, it is also clear, from placebo-controlled trials, that GH replacement therapy can normalize body composition, increase bone mineral content and improve the cardiovascular risk factor profile. GH replacement therapy also improves cardiac performance and exercise capacity, increases muscle strength and improves well-being and quality of life.
The aim of Growth Hormone is to provide a critical update of current knowledge about adult GHD and the future role of GH/IGF-1 in adult medicine. For this purpose, contributions from a number of research groups have been invited. It is my hope that the book may not only serve as an introduction to the field, but also stimulate further research within this exciting area.
Editors and Affiliations
Bibliographic Information
Book Title: Growth Hormone
Editors: Bengt-Åke Bengtsson
Series Title: Endocrine Updates
DOI: https://doi.org/10.1007/978-1-4615-5163-8
Publisher: Springer New York, NY
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eBook Packages: Springer Book Archive
Copyright Information: Springer Science+Business Media New York 1999
Hardcover ISBN: 978-0-7923-8478-6Published: 31 May 1999
Softcover ISBN: 978-1-4613-7351-3Published: 02 November 2012
eBook ISBN: 978-1-4615-5163-8Published: 06 December 2012
Series ISSN: 1566-0729
Edition Number: 1
Number of Pages: XIII, 359
Topics: Endocrinology, Diabetes, Cardiology, Internal Medicine, Orthopedics