Peptides

1. Front Matter

   Pages i-xx

   PDF

2. Novel Approach on Synthetic Method

   1. Orthogonal ligation of free peptides

      • James P. Tam, Yi-An Lu, Qitao Yu

      Pages 3-13

   2. Solid phase synthesis of peptide aldehydes

      • Jean-Alain Fehrentz, Marielle Paris, Annie Heitz, Marc Rolland, Jean Martinez

      Pages 8-13

   3. Investigation of enzyme activity and inhibition in the interior of novel solid supports

      • Morten Meldal, Phaedria M.St. Hilaire, Marianne Willert, Jörg Rademann, Morten Grötli, Jens Buchardt et al.

      Pages 14-20

   4. Immobilization of α-Chymotrypsin on zeolite for peptide synthesis in organic solvent

      • Yun-Hua Ye, Guo-Wen Xing, Gui-Ling Tian, Chong-Xi Li

      Pages 21-25

   5. Preparation of a peptide thioester using a fluoren-9-ylmethoxycarbonyl solid-phase method

      • Xiang-Qun Li, Toru Kawakami, Saburo Aimoto

      Pages 26-29

   6. Application of DEPBT for the synthesis of N-protected peptide alcohols

      • Gui-Ling Tian, Bin-Yuan Sun, Wei Wang, Yun-Hua Ye

      Pages 30-32

   7. Decomposition of amino acid cupric complex by using tetrahydrothiazole-2-thione for preparation of Nα-Boc-Nε-Fmoc-L-Lysine

      • Xing-Ming Gao, Yun-Hua Ye, Gui-Ling Tian, Ding Wang

      Pages 33-35

   8. Two-step selective formation of three disulfide bridges in the synthesis of δ-Gonotoxin PVIA

      • Hui Jiang, Chong-Xu Fan, Zheng-Wei Miao, Kai-Hua Wei, Da-Yu Li, Ming-Nai Zhonga et al.

      Pages 36-39

3. Structure, Folding and Conformation Analysis De novo design of peptide & protein

   1. Design, synthesis and NMR structure of a rigid cyclic peptide template

      • Steven A. Muhle, James P. Tam

      Pages 43-47

   2. Automated docking of Sch68631 with HCV NS3 protease

      • Xiao-Jie Xu, Ting-Jun Hou, Li-Rong Chen, Zheng Li, Jia-Quan Wang

      Pages 48-50

   3. Molecular modeling of the three-dimensional structure of the human interleukin-11

      • Ei-Rong Chen, Ting-Jun Hou, Xiao-Jie Xu, Zheng Li, Jia-Quan Wang

      Pages 51-54

   4. Designing β-hairpin forming short peptide

      • Yin-Lin Sha, Yong-Liang Huang, Qi Wang, Lu-Hua Lai

      Pages 55-58

   5. Anti-tumor activities of papavor somniferum pollen peptides

      • Jia-Xi Xu, Sheng Jin

      Pages 59-61

   6. Structural investigation of two pollen peptides by 2 D homonuclear NMR spectroscopy

      • Yan-Ling Song, Jin-Feng Wang, Er-Cheng Li, Ze-Chuan Qu

      Pages 62-64

   7. A comparison of three heuristic algorithms for molecular docking

      • Ting-Jun Hou, Xiao-Jie Xu, Li-Rong Chen

      Pages 65-68

   8. Aggregation of a calmodulin-binding peptide

      • Hu-Sheng Yan, Xiao-Hui Cheng, Ai-Guo Ni, Bing-Lin He

      Pages 69-72

4. Neuro/Endocrino/Bioactive Peptide

   1. Neuropepxide AVP(4–8) playing an indirect neurotrophic role

      • Qing-Wu Yan, Xiao-Guang Zhen, Tong-Xi Wang, Yu-Cang Du

      Pages 75-76

   2. Potent bradykinin antagonists having medical potential

      • John M. Stewart, Lajos Gera, Eunice J. York, Daniel C. Chan

      Pages 77-80

   3. Understanding the chemistry and biology of rodent relaxin: Role of the C-peptide

      • John D Wade, Nicola F Dawson, Mary Macris, Marc Mathieu, Yean-Yeow Tan, Roger J Summers et al.

      Pages 81-84

The Fifth Chinese Peptide Symposium, hosted by Lanzhou University, was held at Lanzhou, China July 14-17, 1998, with 156 participants, including 30 scientists from abroad, representing nine countries. The four-day conference was both intense and spiritually rewarding. Our goal for CPS-98 was to provide a forum for the exchange of knowledge, cooperation and friendship between the international and Chinese scientific communities, and we believe this goal was met. The symposium consisted of 8 sessions with 42 oral and 90 poster presentations, including synthetic methods, molecular diversity and peptide libraries, structure and conformation of peptides and proteins, bioactive peptides, peptide immunology, De Novo design and synthesis of proteins and peptides, ligand-receptor interactions, the chemistry-biology-interface and challenging problems in peptides. The enthusiastic cooperation and excellent contributions were gratifying and the active response of the invited speakers contributed to the success of the symposium. The presentations were of excellent caliber and represented the most current and significant aspects of peptide science. Dr. Kit Lam of the University of Arizona and Dr. Yun-Hua Ye of Peking University were the recipients of “The Cathay Award” sponsored by the H. H. Liu Education Foundation, offered for their seminal contribution in peptide science and the Chinese Peptide Symposium. Four outstanding young scientists were selected by the organizing committee to receive awards sponsored by Haikou Nanhai Pharmaceutical Industry Co. Ltd. (Zhong He Group).

• Amino acid
• Polybuten
• Polycarbonat
• Tumor
• biology
• enzymes

• Department of Biochemistry and Molecular Biology, School of Life Science, Lanzhou University, Lanzhou, China

  Xiao-Yu Hu, Rui Wang

• Department of Microbiology and Immunology, Vanderbilt University, Nashville, USA

  James P. Tam

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