Nato Science Partnership Subseries: 3

Technological and Medical Implications of Metabolic Control Analysis

Editors: Cornish-Bowden, Athel, Cárdenas, Maria Luz (Eds.)

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eBook $119.00
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  • ISBN 978-94-011-4072-0
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Softcover $159.00
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About this book

Two decades have passed since the mechanisms of protein synthesis became well enough understood to permit the genetic modification oforganisms. An impressive amount of new knowledge has emerged from the new technology, but much ofthe promise of20years ago has notyet been fulfilled. In biotechnology, efforts to increase the yields of commercially valuable metabolites have been less successful than ex­ pected, and when they have succeeded it has often been as much from selective breeding as from new methods. The cell is more complicated than what is presented in the classical teaching of biochemistry, it contains more structure than was dreamed of 20 years ago, and the behaviour ofany systemofenzymes is more elaborate than can be explained in terms ofa single supposedly rate-limiting enzyme. Even if classical enzymology and meta­ bolism may have seemed rather unfashionable during the rise ofmolecular biology, they remain central to any modification ofthe metabolic behaviour oforganisms. As such modification is essential in much ofbiotechnology and drug development, bio­ technologists can only ignore these topics at their peril.

Table of contents (38 chapters)

  • Snapshots of Systems

    Kell, Douglas B. (et al.)

    Pages 3-25

  • Moiety Conservation and Flux Enhancement

    Rohwer, Johann M. (et al.)

    Pages 27-32

  • On the Universality of The Universal Method

    Acerenza, Luis

    Pages 33-37

  • Life is Complicated

    Bailey, James E.

    Pages 41-47

  • Regulation and Redirection of Metabolism: Incorporating regulatory information influx calculation

    Liao, James C.

    Pages 49-56

Buy this book

eBook $119.00
price for USA in USD (gross)
  • ISBN 978-94-011-4072-0
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $159.99
price for USA in USD
  • ISBN 978-0-7923-6188-6
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $159.00
price for USA in USD
  • ISBN 978-0-7923-6189-3
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Technological and Medical Implications of Metabolic Control Analysis
Editors
  • Athel Cornish-Bowden
  • Maria Luz Cárdenas
Series Title
Nato Science Partnership Subseries: 3
Series Volume
74
Copyright
2000
Publisher
Springer Netherlands
Copyright Holder
Springer Science+Business Media Dordrecht
eBook ISBN
978-94-011-4072-0
DOI
10.1007/978-94-011-4072-0
Hardcover ISBN
978-0-7923-6188-6
Softcover ISBN
978-0-7923-6189-3
Series ISSN
1388-6576
Edition Number
1
Number of Pages
XIV, 374
Number of Illustrations and Tables
82 b/w illustrations
Topics