Cytotoxic, Mutagenic and Carcinogenic Potential of Heavy Metals Related to Human Environment
Editors: Hadjiliadis, N. (Ed.)
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- About this book
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Environmental pollution is one of the main problems to confront humanity, with the heavy metals occupying a leading role among the most pernicious pollutants. The metals cause cancer and other sicknesses. Their cytotoxic, mutagenic and carcinogenic potentials are not fully understood, and any thorough investigation demands the combined efforts of scientists drawn from many different disciplines. But the effects of heavy metals are not all negative: some, like cis-DDP, and some ruthenium and tin complexes, have antitumour activity.
The idea underlying the present work is therefore to present a multidisciplinary perspective on heavy metals in the environment, affording a better understanding of their action on human organisms and health, aiming to make them less polluting and more environmentally friendly.
- Table of contents (39 chapters)
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Zinc Finger-DNA Interaction: Effect of Metal Replacement, Free Radical Generation and DNA Damage and its Relevance to Carcinogenesis
Pages 1-14
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Pathways in the Chromium(VI)-Mediated Formation of DNA Lesions: A Review
Pages 15-34
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Approaches to the Biological Monitoring of Chromium(VI) Exposed Individuals
Pages 35-53
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The Mechanisms of Metal Carcinogenicity
Pages 55-72
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The Oxidative Damage Hypothesis of Metal-Induced Genotoxicity and Carcinogenesis
Pages 73-92
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Table of contents (39 chapters)
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Bibliographic Information
- Bibliographic Information
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- Book Title
- Cytotoxic, Mutagenic and Carcinogenic Potential of Heavy Metals Related to Human Environment
- Editors
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- N. Hadjiliadis
- Series Title
- Nato Science Partnership Subseries: 2
- Series Volume
- 26
- Copyright
- 1997
- Publisher
- Springer Netherlands
- Copyright Holder
- Springer Science+Business Media Dordrecht
- eBook ISBN
- 978-94-011-5780-3
- DOI
- 10.1007/978-94-011-5780-3
- Hardcover ISBN
- 978-0-7923-4432-2
- Softcover ISBN
- 978-94-010-6440-8
- Series ISSN
- 1389-1839
- Edition Number
- 1
- Number of Pages
- XXIV, 629
- Topics
