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Methodology for Genetic Studies of Twins and Families

  • Book
  • © 1992

Overview

Authors:
  1. Michael C. Neale

    1. Department of Human Genetics, Medical College of Virginia, Virginia Commonwealth University, Richmond, USA

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    You can also search for this author in PubMed   Google Scholar

  2. Lon R. Cardon

    1. Institute for Behavioral Genetics, University of Colorado, Boulder, USA

    View author publications

    You can also search for this author in PubMed   Google Scholar

Part of the book series: NATO Science Series D: (ASID, volume 67)

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Table of contents (18 chapters)

  1. Front Matter

    Pages i-xxv
    Download chapter PDF

  2. The Scope of Genetic Analyses

    • Michael C. Neale, Lon R. Cardon
    Pages 1-33

  3. Data Summary

    • Michael C. Neale, Lon R. Cardon
    Pages 35-53

  4. Biometrical Genetics

    • Michael C. Neale, Lon R. Cardon
    Pages 55-70

  5. Matrix Algebra

    • Michael C. Neale, Lon R. Cardon
    Pages 71-86

  6. Path Analysis and Structural Equations

    • Michael C. Neale, Lon R. Cardon
    Pages 87-108

  7. LISREL Models and Methods

    • Michael C. Neale, Lon R. Cardon
    Pages 109-130

  8. Model Fitting Functions and Optimization

    • Michael C. Neale, Lon R. Cardon
    Pages 131-148

  9. Univariate Analysis

    • Michael C. Neale, Lon R. Cardon
    Pages 149-187

  10. Power and Sample Size

    • Michael C. Neale, Lon R. Cardon
    Pages 189-197

  11. Social Interaction

    • Michael C. Neale, Lon R. Cardon
    Pages 199-210

  12. Sex-limitation and G × E Interaction

    • Michael C. Neale, Lon R. Cardon
    Pages 211-229

  13. Multivariate Analysis

    • Michael C. Neale, Lon R. Cardon
    Pages 231-259

  14. Direction of Causation

    • Michael C. Neale, Lon R. Cardon
    Pages 261-287

  15. Repeated Measures

    • Michael C. Neale, Lon R. Cardon
    Pages 289-304

  16. Longitudinal Mean Trends

    • Michael C. Neale, Lon R. Cardon
    Pages 305-311

  17. Observer Ratings

    • Michael C. Neale, Lon R. Cardon
    Pages 313-327

  18. Assortment and Cultural Transmission

    • Michael C. Neale, Lon R. Cardon
    Pages 329-351

  19. Future Directions

    • Michael C. Neale, Lon R. Cardon
    Pages 353-372

  20. Back Matter

    Pages 373-496
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Keywords

About this book

Few would dispute the truth of the statement `People are Different', but there is much controversy over why. This book authoritatively explains the methods used to understand human variation, and extends them far beyond the primary `nature or nurture' question. After chapters on basic statistics, biometrical genetics, matrix algebra and path analysis, there is a state-of-the-art account of how to fit genetic models using the LISREL package.
The authors explain not only the assumptions of the twin method, but how to test them. The elementary model is expanded to cover sex limitation, sibling interaction, multivariate and longitudinal data, observer ratings, and twin-family studies. Throughout, the methods are illustrated by applications to diverse areas such as obesity, major depression, alcohol comsumption, delinquency, allergies, and common fears.

Authors and Affiliations

  • Department of Human Genetics, Medical College of Virginia, Virginia Commonwealth University, Richmond, USA

    Michael C. Neale

  • Institute for Behavioral Genetics, University of Colorado, Boulder, USA

    Lon R. Cardon

Bibliographic Information

  • Book Title: Methodology for Genetic Studies of Twins and Families

  • Authors: Michael C. Neale, Lon R. Cardon

  • Series Title: NATO Science Series D:

  • DOI: https://doi.org/10.1007/978-94-015-8018-2

  • Publisher: Springer Dordrecht

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer Science+Business Media Dordrecht 1992

  • Hardcover ISBN: 978-0-7923-1874-3Published: 31 July 1992

  • Softcover ISBN: 978-90-481-4179-1Published: 05 December 2010

  • eBook ISBN: 978-94-015-8018-2Published: 09 March 2013

  • Series ISSN: 0258-123X

  • Edition Number: 1

  • Number of Pages: XXVI, 496

  • Topics: Human Genetics, Methodology of the Social Sciences

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