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Developments in Cardiovascular Medicine

Pathophysiology of Severe Ischemic Myocardial Injury

Editors: Piper, H.M. (Ed.)

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About this book

In industrialized countries, ischemic heart disease is by far the most common organ-specific cause of death. The thrombotic occlusion of a coronary artery which had previously been severely altered by atherosclerosis, is the most frequent cause of ischemic deterioration of myocardial tissue, i. e. myocardial infarction. Death of the human individual occurs when myocardial ischemia causes a critical impairment of cardiac pump function. The failure of a heart with an ischemic area may be due to the amount and location of contractile tissue becoming paralyzed or even necrotic, or to arrhythmias provoked by the ischemic condition, or by a combination of both factors. Considerable progress has been made in the development of antiarrythmic therapy. Effective tools have been developed to reperfuse ischemic myocar­ dial tissue as soon as the patient reaches hospital. However, therapeutical principles for the ischemic-reperfused myocardium which would specifically interfere with the state of injury of the ischemic tissue at the onset of reperfusion, and avoid the apparent hazards of the reperfusion process itself, have yet to be established. But not only approved therapeutical concepts are lacking, the pathophysiology of myocardial cell injury in pro­ gressive ischemia and under reperfusion is in itself only partly understood.

Reviews

`... it undoubtedly provides up-to-date knowledge and should prove a valuable source of reference.'
Cardiology Today, 19:1, 1991

Table of contents (20 chapters)

Table of contents (20 chapters)

Buy this book

eBook $59.99
price for USA in USD
  • ISBN 978-94-009-0475-0
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $99.00
price for USA in USD
  • ISBN 978-0-7923-0459-3
  • Free shipping for individuals worldwide
  • Immediate ebook access, if available*, with your print order
  • This title is currently reprinting. You can pre-order your copy now.
Softcover $79.99
price for USA in USD
  • ISBN 978-94-010-6699-0
  • Free shipping for individuals worldwide
  • Immediate ebook access, if available*, with your print order
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Pathophysiology of Severe Ischemic Myocardial Injury
Editors
  • H.M. Piper
Series Title
Developments in Cardiovascular Medicine
Series Volume
104
Copyright
1990
Publisher
Springer Netherlands
Copyright Holder
Kluwer Academic Publishers
eBook ISBN
978-94-009-0475-0
DOI
10.1007/978-94-009-0475-0
Hardcover ISBN
978-0-7923-0459-3
Softcover ISBN
978-94-010-6699-0
Series ISSN
0166-9842
Edition Number
1
Number of Pages
440
Topics

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