Control of Enzyme Activity

1. Front Matter

   Pages 1-6

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2. Introduction

   • Philip Cohen

   Pages 7-8

3. Regulation of amino acid and nucleotide biosynthesis in bacteria by end product inhibition

   • Philip Cohen

   Pages 9-24

4. The initiation of biological function by limited proteolysis

   • Philip Cohen

   Pages 25-41

5. Enzyme regulation by reversible phosphorylation: the neural and hormonal control of cellular activity

   • Philip Cohen

   Pages 42-71

6. Control of enzyme activity by covalent modifications other than limited proteolysis or phosphorylation

   • Philip Cohen

   Pages 72-88

7. The nature of the allosteric transition

   • Philip Cohen

   Pages 89-94

8. Back Matter

   Pages 94-96

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The student of biological science in his final years as an undergraduate and his first years as a graduate is expected to gain some familiarity with current research at the frontiers of his discipline. New research work is published in a perplexing diversity of publications and is inevitably concerned with the minutiae of the subject. The sheer number of research journals and papers also causes confusion and difficulties of assimilation. Review articles usually presuppose a background knowledge of the field and are inevitably rather restricted in scope. There is thus a need for short but authoritative introductions to those areas of modern biological research which are either not dealt with in standard introductory textbooks or are not dealt with in sufficient detail to enable the student to go on from them to read scholarly reviews with profit. This series of books is designed to satisfy this need. The authors have been asked to produce a brief outline of their subject assuming that their readers will have read and remembered much of a standard introductory textbook of biology.

• Nucleotide
• amino acid
• bacteria
• biology
• enzyme
• enzymes
• phosphorylation
• synthesis

This is a useful little book and in fact despite its small size it is packed with information...The book covers a wide range of up-to-date biochemistry. The index is quite comprehensive and the diagrams clear and simple. Biochemical Education; The first edition was good, but this update is even better. Professor Cohen has produced an eminently readable little book that provides an invaluable pocket guide to all those interested in the regulation of enzyme activity..It will undoubtedly be essential reading for undergraduates and is a worthy addition to anyone's library. TIBS

• Department of Biochemistry, University of Dundee, UK

  Philip Cohen

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