Human Protein Metabolism

1. Front Matter

   Pages i-xi

   PDF

2. The Importance of Protein Dynamics

   • Stephen Welle

   Pages 1-10

3. Basic Mechanisms of Protein Turnover

   • Stephen Welle

   Pages 11-28

4. Methods for Studying Protein Metabolism in Humans

   • Stephen Welle

   Pages 29-71

5. Normative Data from Infancy to Old Age

   • Stephen Welle

   Pages 72-90

6. Nutritional Influences

   • Stephen Welle

   Pages 91-123

7. Endocrine, Paracrine, and Autocrine Regulation

   • Stephen Welle

   Pages 124-160

8. Regulation by Metabolic Substrates

   • Stephen Welle

   Pages 161-176

9. Physical Activity

   • Stephen Welle

   Pages 177-195

10. Topics of Clinical Interest

    • Stephen Welle

    Pages 196-227

11. Back Matter

    Pages 228-288

    PDF

Human Protein Metabolism is a succinct review of hundreds of studies on the regulation of protein mass and protein turnover in the human body. The biochemistry of protein synthesis and breakdown is summarized, and the methods that are used to examine protein metabolism in humans are explained, and their limitations discussed. The book includes chapters that review the effects of nutrition, hormones, metabolic substrates, and physical activity. Various topics of clinical interest are covered, including cancer, diabetes, tissue injury, pregnancy, renal disease, muscular dystrophies, and other conditions. Normal values are presented for turnover of proteins in the whole body and individual organs, and for turnover of many individual proteins. This book will be a valuable resource for physiologists, nutritionists, and clinicians interested in the regulation of body protein stores in health and disease. For scientists primarily interested in the basic aspects of protein metabolism, it shows how the basic knowledge is being applied to the study of humans.

• AIDS
• Amino acid
• HIV
• Oxidation
• biochemistry
• influence
• metabolism
• prostaglandins
• protein structure
• proteins
• regulation
• surgery
• tissue
• translation

• Endocrine Metabolism Unit Monroe Community Hospital, University of Rochester Medical Center, Rochester, USA

  Stephen Welle

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