Implantable Neural Prostheses 2

1. Front Matter

   Pages i-xiii

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2. The Biocompatibility and Biostability of New Cardiovascular Materials and Devices

   • Ken Stokes

   Pages 1-26

3. Technology Advances and Challenges in Hermetic Packaging for Implantable Medical Devices

   • Guangqiang Jiang, David D. Zhou

   Pages 27-61

4. Science and Technology of Bio-Inert Thin Films as Hermetic-Encapsulating Coatings for Implantable Biomedical Devices: Application to Implantable Microchip in the Eye for the Artificial Retina

   • Orlando Auciello, Bing Shi

   Pages 63-84

5. The Electrochemistry of Charge Injection at the Electrode/Tissue Interface

   • Daniel R. Merrill

   Pages 85-138

6. In Situ Characterization of Stimulating Microelectrode Arrays: Study of an Idealized Structure Based on Argus II Retinal implants

   • Vincent Kandagor, Carlos J. Cela, Charlene A. Sanders, Elias Greenbaum, Gianluca Lazzi, David D. Zhou et al.

   Pages 139-156

7. Thin-Film Microelectrode Arrays for Biomedical Applications

   • Karen C. Cheung

   Pages 157-190

8. Stimulation Electrode Materials and Electrochemical Testing Methods

   • Andy Hung, Ira B. Goldberg, Jack W. Judy

   Pages 191-216

9. Conducting Polymers in Neural Stimulation Applications

   • David D. Zhou, X. Tracy Cui, Amy Hines, Robert J. Greenberg

   Pages 217-252

10. Microelectronics of Recording, Stimulation, and Wireless Telemetry for Neuroprosthetics: Design and Optimization

    • Moo Sung Chae, Zhi Yang, Wentai Liu

    Pages 253-330

11. Microchip-Embedded Capacitors for Implantable Neural Stimulators

    • Orlando Auciello

    Pages 331-344

12. An Effective Design Process for the Successful Development of Medical Devices

    • Mike Colvin

    Pages 345-359

13. Back Matter

    Pages 1-13

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Signi?cant progress has been made in the development of neural prostheses for restoration of human functions and improvement of the quality of life. Biomedical engineers and neuroscientists around the world are working to improve the design and performance of existing devices and to develop novel devices for arti?cial vision, arti?cial limbs, and brain-machine interfaces. This book, Implantable Neural Prostheses 2: Techniques and Engineering Approaches, is part two of a two-volume sequence that describes state-of-the-art advances in techniques associated with implantable neural prosthetic devices. The techniques covered include biocompatibility and biostability, hermetic packaging, electrochemical techniques for neural stimulation applications, novel electrode materials and testing, thin-?lm ?exible microelectrode arrays, in situ char- terization of microelectrode arrays, chip-size thin-?lm device encapsulation, microchip-embedded capacitors and microelectronics for recording, stimulation, and wireless telemetry. The design process in the development of medical devices is also discussed. Advances in biomedical engineering, microfabrication technology, and neu- science have led to improved medical-device designs and novel functions. However, many challenges remain. This book focuses on the engineering approaches, R&D advances, and technical challenges of medical implants from an engineering p- spective. We are grateful to leading researchers from academic institutes, national laboratories, as well as design engineers and professionals from the medical device industry who have contributed to the book. Part one of this series covers designs of implantable neural prosthetic devices and their clinical applications.

• Biomedical application
• Implantable Device
• Medtronic
• Motor Prosthetic Devices
• Neural Prosthetic Technique
• Prosetheses
• Prosthetic Device
• Sensory Motor Device
• biomedical applications
• medical devices
• tissue

From the book reviews:

“It is my pleasure to highly recommend this book for a comprehensive discussion of cortical, optic nerve, lateral geniculate, and retinal prostheses as it relates to vision and hearing. … I recommend this book highly for engineers, students, fellows and investigators at advanced levels.” (Joseph J. Grenier, Amazon.com, December, 2014)

• Second Sight Medical Products, Inc., Sylmar, USA

  David Zhou

• Oak Ridge National Laboratory, Oak Ridge, USA

  Elias Greenbaum

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