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Ovarian Cancer

Second Edition

  • Book
  • © 2010

Overview

Editors:
  1. M. Sharon Stack

    1. School of Medicine, University of Missouri, Columbia, U.S.A.

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    You can also search for this editor in PubMed   Google Scholar

  2. David A. Fishman

    1. School of Medicine, New York University, New York, U.S.A.

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  • New advances in ovarian cancer detection and treatment
  • Provides an analysis of current research into aspects of malignant transformation, growth control and metastasis
  • Includes supplementary material: sn.pub/extras

Part of the book series: Cancer Treatment and Research (CTAR, volume 149)

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Table of contents (17 chapters)

  1. Front Matter

    Pages i-xv
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  2. Chemoprevention, Staging, and Novel Therapeutic Targets

    1. Front Matter

      Pages 1-1
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    2. Chemoprevention of Ovarian Cancer

      • Anna Hoekstra, Gustavo C. Rodriguez
      Pages 3-34

    3. Staging and Surgical Treatment

      • Mario M. Leitao Jr, Richard R. Barakat
      Pages 35-61

    4. Novel Therapeutic Targets

      • John Farley, Michael J. Birrer
      Pages 63-84

    5. Biomarker Targets and Novel Therapeutics

      • Mary Clouser, Lisa M. Hess, Setsuko K. Chambers
      Pages 85-105

  3. Tumorigenesis and Biomarkers

    1. Front Matter

      Pages 107-107
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    2. Tumor Suppressor Genes

      • Zhen Lu, Robert C. Bast Jr
      Pages 109-129

    3. Epigenetics and Ovarian Cancer

      • Kenneth P. Nephew, Curt Balch, Shu Zhang, Tim H-M. Huang
      Pages 131-146

    4. Aberrant Epithelial Differentiation in Ovarian Cancer

      • Elizabeth R. Smith, Kathy Qi Cai, Callinice D. Capo-chichi, Xiang- Xi Xu
      Pages 147-163

    5. The Human Kallikrein Gene Family: New Biomarkers for Ovarian Cancer

      • George M. Yousef, Eleftherios P. Diamandis
      Pages 165-187

    6. Soluble Epidermal Growth Factor Receptor: A Biomarker of Epithelial Ovarian Cancer

      • Andre T. Baron, Jacqueline M. Lafky, Cecelia H. Boardman, Elsa M. Cora, Marites C. Buenafe, Dachao Liu et al.
      Pages 189-202

    7. Activated Epidermal Growth Factor Receptor in Ovarian Cancer

      • Laurie G. Hudson, Reema Zeineldin, Melina Silberberg, M. Sharon Stack
      Pages 203-226

  4. Tumor Progression, Metastasis, Research Models

    1. Front Matter

      Pages 227-227
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    2. Ras-Superfamily GTP-ases in Ovarian Cancer

      • Kwai Wa Cheng, Roshan Agarwal, Gordon B. Mills
      Pages 229-240

    3. Lipid Generation and Signaling in Ovarian Cancer

      • Yan Xu, Dongmei Wang, Zeneng Wang
      Pages 241-267

    4. Lysophosphatidic Acid and Invasion

      • Fengqiang Wang, David A. Fishman
      Pages 269-296

    5. Cell Adhesion in Ovarian Cancer

      • Wafic M. ElMasri, Giovanna Casagrande, Ebony Hoskins, Daniel Kimm, Elise C. Kohn
      Pages 297-318

    6. Microenvironmental Regulation of Ovarian Cancer Metastasis

      • Maria V. Barbolina, Natalie M. Moss, Suzanne D. Westfall, Yueying Liu, Rebecca J. Burkhalter, Francoise Marga et al.
      Pages 319-334

    7. Organotypic Models of Metastasis: A Three-dimensional Culture Mimicking the Human Peritoneum and Omentum for the Study of the Early Steps of Ovarian Cancer Metastasis

      • Hilary A. Kenny, Songuel Dogan, Marion Zillhardt, Anirban K. Mitra, S. Diane Yamada, Thomas Krausz et al.
      Pages 335-351
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Keywords

About this book

Ovarian carcinoma continues to be responsible for more deaths than all other gynecologic malignancies combined, due to a continued inability to achieve detection of early (rather than advanced) stage disease and the lack of effective tumor-specific therapeutics.

Ovarian carcinogenesis, invasion, and metastatic dissemination require a complex cascade of interrelated genetic, molecular, and biochemical events that regulate the neoplastic transition of normal ovarian surface epithelium.

This updated second edition includes exciting new advances in ovarian cancer detection and treatment and provides an analysis of current research into aspects of malignant transformation, growth control, and metastasis. A more detailed understanding of these processes may ultimately translate into the development of novel approaches for the detection and control of ovarian cancer.

Reviews

From the reviews of the second edition:

“This is a book for basic scientists and clinicians that addresses the pertinent translational and basic science issues concerning ovarian cancer. It is insightful and written at the highest level. … It is intended for basic scientists and clinicians who have questions surrounding the issues around ovarian cancer. … This outstanding and readable book covers many of the basic science and translational science issues involved in ovarian cancer.” (David G. Mutch, Doody’s Review Service, April, 2011)

Editors and Affiliations

  • School of Medicine, University of Missouri, Columbia, U.S.A.

    M. Sharon Stack

  • School of Medicine, New York University, New York, U.S.A.

    David A. Fishman

Bibliographic Information

  • Book Title: Ovarian Cancer

  • Book Subtitle: Second Edition

  • Editors: M. Sharon Stack, David A. Fishman

  • Series Title: Cancer Treatment and Research

  • DOI: https://doi.org/10.1007/978-0-387-98094-2

  • Publisher: Springer New York, NY

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Springer-Verlag US 2010

  • Hardcover ISBN: 978-0-387-98093-5Published: 27 October 2009

  • Softcover ISBN: 978-1-4614-2473-4Published: 25 February 2012

  • eBook ISBN: 978-0-387-98094-2Published: 18 September 2009

  • Series ISSN: 0927-3042

  • Series E-ISSN: 2509-8497

  • Edition Number: 2

  • Number of Pages: XVI, 408

  • Number of Illustrations: 12 b/w illustrations, 32 illustrations in colour

  • Topics: Oncology, Gynecology, Cancer Research, Human Genetics

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