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Transcriptional Regulation by Neuronal Activity

To the Nucleus and Back

Editors:

  • Comprehensive chapters give readers an up-to-date picture of the field
  • Covers a variety of methods and topics, including signal initiation and transduction to the nucleus and possible functions of the activity-regulated genes
  • Focuses on the rapidly-evolving area of activity regulation of gene transcription

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Table of contents (19 chapters)

  1. Front Matter

    Pages I-XII
  2. Activity-regulated Transcription: Getting to the Nucleus

    1. Front Matter

      Pages 1-1
    2. Transcriptional Regulation of Activity-Dependent Genes by Birdsong

      • Tarciso A.F. Velho, Claudio V. Mello
      Pages 3-26
    3. To the Nucleus with Proteomics

      • Bryen A. Jordan, Edward B. Ziff
      Pages 27-50
    4. Intracellular Calcium Waves Transmit Synaptic Information to the Nucleus in Hippocampal Pyramidal Neurons

      • Mark F. Yeckel, Amanda A. Sleeper, John S. Fitzpatrick, Daniel N. Hertle, Anna M. Hagenston, Robin T. Garner
      Pages 73-89
    5. Role of Action Potentials in Regulating Gene Transcription: Relevance to LTP

      • J. Paige Adams, Rachel A. Robinson, Serena M. Dudek
      Pages 91-110
    6. L-type Channel Regulation of Gene Expression

      • Natalia Gomez-Ospina, Ricardo Dolmetsch
      Pages 111-123
  3. Activity-regulated Transcription: Gene Regulation

    1. Front Matter

      Pages 125-125
    2. CREB-Dependent Transcription and Synaptic Plasticity

      • Angel Barco, Dragana Jancic, Eric R. Kandel
      Pages 127-154
    3. Activity-Dependent Bigenomic Transcriptional Regulation of Cytochrome c Oxidase in Neurons

      • Margaret T.T. Wong-Riley, Huan Ling Liang, Sakkapol Ongwijitwat
      Pages 209-228
  4. Activity-regulated Transcription: Role in Nervous System Function

    1. Front Matter

      Pages 251-251
    2. Synaptic Growth and Transcriptional Regulation in Drosophila

      • Cynthia Barber, J. Troy Littleton
      Pages 253-275
    3. Transcriptional Mechanisms Underlying the Mammalian Circadian Clock

      • Hai-Ying Mary Cheng, Karl Obrietan
      Pages 313-336

About this book

Regulation of gene transcription by neuronal activity is evident in a large number of neuronal processes ranging from neural development and refinement of neuronal connections to learning and response to injury. In the field of activity-dependent gene expression, rapid progress is being made that can impact these, and many other areas of neuroscience. The major aim of Transcriptional Regulation by Neuronal Activity: To the Nucleus and Back is to illustrate key advances in the field – specifically how signals are transmitted to the nucleus in response to neuronal activity, what genes are activated and how this is achieved, and how these changes in gene expression alter neuronal function.

Editors and Affiliations

  • Laboratory of Neurobiology, Synaptic & Developmental Plasticity Group NIEHS/NIH, Research Triangle Park, USA

    Serena M. Dudek

Bibliographic Information

  • Book Title: Transcriptional Regulation by Neuronal Activity

  • Book Subtitle: To the Nucleus and Back

  • Editors: Serena M. Dudek

  • DOI: https://doi.org/10.1007/978-0-387-73609-9

  • Publisher: Springer New York, NY

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Springer-Verlag US 2008

  • Hardcover ISBN: 978-0-387-73608-2Published: 12 November 2007

  • Softcover ISBN: 978-1-4419-4463-4Published: 04 November 2010

  • eBook ISBN: 978-0-387-73609-9Published: 24 November 2007

  • Edition Number: 1

  • Number of Pages: XII, 425

  • Topics: Neurosciences, Neurology, Neurobiology

Buy it now

Buying options

eBook USD 129.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 169.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access