Oncofertility

1. Front Matter

   Pages i-xviii

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2. Introduction

   1. Front Matter

      Pages 1-1

      PDF

   2. The Emergence of a New Interdiscipline: Oncofertility

      • Teresa K. Woodruff

      Pages 3-11

3. Fertility Risk and Treatment Options

   1. Front Matter

      Pages 13-13

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   2. Fertility Management for Women With Cancer

      • Sanjay K. Agarwal, R. Jeffrey Chang

      Pages 15-27

   3. Fertility Preservation in Adult Male Cancer Patients

      • Robert E. Brannigan

      Pages 28-49

   4. Managing Fertility in Childhood Cancer Patients

      • Kimberley J. Dilley

      Pages 50-56

   5. Fertility Risk in Pediatric and Adolescent Cancers

      • Clarisa R. Gracia, Jill P. Ginsberg

      Pages 57-72

4. Oncofertility Techniques and Research

   1. Front Matter

      Pages 73-73

      PDF

   2. Bioengineering and the Ovarian Follicle

      • Min Xu, Teresa K. Woodruff, Lonnie D. Shea

      Pages 75-82

   3. The Science of Cryobiology

      • Steven F. Mullen, John K. Critser

      Pages 83-109

   4. Ovarian Tissue Cryopreservation and Transplantation: Banking Reproductive Potential for the Future

      • David Lee

      Pages 110-129

   5. Progress, History and Promise of Ovarian Cryopreservation and Transplantation for Pediatric Cancer Patients

      • Yasmin Gosiengfiao

      Pages 130-134

5. Health Care Decision-Making

   1. Front Matter

      Pages 135-135

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   2. Oncofertility and the Social Sciences

      • Karrie Ann Snyder

      Pages 137-148

   3. Shared Decision Making: Fertility and Pediatric Cancers

      • Marla L. Clayman, Kathleen M. Galvin, Paul Arntson

      Pages 149-160

6. Ethical and Psychosocial Impact of Cancer-Related Infertility

   1. Front Matter

      Pages 161-161

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   2. Today's Research, Tomorrows Cures: The Ethical Implications of Oncofertility

      • Leilah E. Backhus, Laurie Zoloth

      Pages 163-179

   3. The Psychosocial Context of Cancer-Related Infertility

      • Matthew J. Loscalzo, Karen L. Clark

      Pages 180-190

   4. Childhood Cancer: Fertility and Psychosocial Implications

      • Karen E. Kinahan, Aarati Didwania, Carrie L. Nieman

      Pages 191-200

It has been our pleasure to edit the first book on an interdisciplinary science we call oncofertility. Oncofertility bridges traditional areas of basic science and medical research, brings together oncologists and fertility specialists, and hopes to provide real options to young people who survive life-preserving but fertility-threatening treatments for cancer. The chapters in this book range from basic discovery research to reproductive medicine and from social science and the humanities to a section on stories from those who have survived cancer and have faced issues of fertility deprivation or restoration. Specifically, we have addressed three main areas: the underlying biological questions surrounding follicle growth and cryo-preservation of tissue; the application of the new technology to medical practice; and, the psychosocial implications of cancer-related infertility and oncofertility research for patients and their families. These questions are interlinking and require teams of investigators working in concert to solve a major unmet need. The book is a comprehensive initial definition of the field and we anticipate a great many more breakthroughs that will eventually provide a menu of options to those with fertility-threatening conditions. The editors thank the Specialized Cooperative Centers Program in Reproduction and Infertility Research (U54 HD041857) and the Institute for Women’s Health Research of Northwestern University for funding and support of this book. Teresa K.

• cancer
• child
• ethics
• fertility
• fertility preservation, gynecology, cancer/oncology, urology
• gynecology
• infertility
• oncology
• pregnancy
• urology

From the reviews:

"This is a compilation of current research on the preservation of fertility in young cancer patients facing gonadotoxic treatment regimens. … While they have targeted this book at helping to train and educate oncologists and reproductive specialists caring for young cancer patients, it may also be interesting and important to people in a variety of other fields including those in reproductive biology, biomedical ethics, sociology, and health policy. … an interesting and important book for anyone involved in the care of young cancer patients." (Emily S. Jungheim, Doody’s Review Service, January, 2008)

 

"This book is the first of its kind on the topic of oncofertility - a new discipline uniting reproductive biologists with oncologists to provide options for men, women, and children with a fertility-threatening cancer diagnosis. The book spans disciplines from cutting edge research to clinical care, bioethics, and medical guidelines. There are chapters for the specialists and chapters for patients who wish to read stories about those who have faced fertility-impacting diseases."

This is a terrific book and a must read!

Linda C. Giudice, MD, PhD, MSc
Professor and Chair, Department of Obstetrics, Gynecology and Reproductive Sciences
The Robert B. Jaffe, MD, Endowed Professor in Reproductive Sciences
University of California, San Francisco

• Northwestern University, Chicago, USA

  Teresa K. Woodruff, Karrie Ann Snyder

Policies and ethics