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Shh and Gli Signalling in Development

  • Book
  • © 2007

Overview

Authors:
  1. Carolyn E. Fisher

    1. Immunobiology Group MRC/UoE Centre for Inflammation Research, The Queen’s Medical Research Institute, Edinburgh, UK

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  2. Sarah E. M. Howie

    1. Immunobiology Group MRC/UoE Centre for Inflammation Research, The Queen’s Medical Research Institute, Edinburgh, UK

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    You can also search for this author in PubMed   Google Scholar

  • Useful for post-doctoral researchers and post-graduate research students working on Shh signalling in a particular organ

Part of the book series: Molecular Biology Intelligence Unit (MBIU)

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Table of contents (14 chapters)

  1. Front Matter

    Pages i-x
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  2. Introduction

    • Carolyn E. Fisher, Sarah E.M. Howie
    Pages 1-11

  3. Sonic Hedgehog Signalling in Dorsal Midline and Neural Development

    • Silvia L. López, Andrés E. Carrasco
    Pages 12-22

  4. Role of Hedgehog and Gli Signalling in Telencephalic Development

    • Paulette A. Zaki, Ben Martynoga, David J. Price
    Pages 23-35

  5. Role of Shh and Gli Signalling in Oligodendroglial Development

    • Min Tan, Yingchuan Qi, Mengsheng Qiu
    Pages 36-43

  6. The Role of Sonic Hedgehog Signalling in Craniofacial Development

    • Dwight Cordero, Minal Tapadia, Jill A. Helms
    Pages 44-57

  7. Multiple Roles for Hedgehog Signalling in Zebrafish Eye Development

    • Deborah L. Stenkamp
    Pages 58-68

  8. Sonic Hedgehog Signalling during Tooth Morphogenesis

    • Martyn T. Cobourne, Isabelle Miletich, Paul T. Sharpe
    Pages 69-78

  9. Limb Pattern Formation

    • Aimée Zuniga, Antonella Galli
    Pages 79-92

  10. Sonic Hedgehog Signalling in the Developing and Regenerating Fins of Zebrafish

    • Fabien Avaron, Amanda Smith, Marie-Andrée Akimenko
    Pages 93-106

  11. Hedgehog Signalling in T Lymphocyte Development

    • Susan Outram, Ariadne L. Hager-Theodorides, Tessa Crompton
    Pages 107-115

  12. Hedgehog Signalling in Prostate Morphogenesis

    • Marilyn L. G. Lamm, Wade Bushman
    Pages 116-124

  13. Sonic Hedgehog Signalling in Visceral Organ Development

    • Huimin Zhang, Ying Litingtung, Chin Chiang
    Pages 125-136

  14. Shh/Gli Signalling during Murine Lung Development

    • Martin Rutter, Martin Post
    Pages 137-146

  15. New Perspectives in Shh Signalling?

    • Carolyn E. Fisher
    Pages 147-154

  16. Back Matter

    Pages 155-158
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Keywords

About this book

he hedgehog signalling pathway is highly conserved and seen in organisms ranging from Drosophila to humans. This pathway is Tcritical in determining cell fate decisions in a variety of different cell types. There are several vertebrate analogues of the Drosophila hedgehog protein of which the most widely studied is Sonic hedgehog (Shh). Shh signalling classically involves the Gli family of zinc-fmger transcription factors. The Shh signalling pathway is well characterised in the develop­ ment of a number of vertebrate organ systems. It could indeed be argued that the Shh and Gli signalling may well be involved at some stage in the development of all the major organ systems in vertebrates. This volume rep­ resents a concerted drive to bring together *state of the art' reviews by lead­ ing experts in the field of Shh and Gli signalling in development from all over the world. The chapters span vertebrate organisms from zebrafish to humans and cover development of the multiple organ systems in which the Shh signalling pathway is crucial for normal development. There are chap­ ters on the development of the central nervous system, skeletal struc­ tures, visceral organs, prostate, lung, immune system and the structures of the human face. The authors themselves span three major continents and multiple nationalities which admirably illustrates the worldwide nature of the science.

Authors and Affiliations

  • Immunobiology Group MRC/UoE Centre for Inflammation Research, The Queen’s Medical Research Institute, Edinburgh, UK

    Carolyn E. Fisher, Sarah E. M. Howie

Bibliographic Information

  • Book Title: Shh and Gli Signalling in Development

  • Authors: Carolyn E. Fisher, Sarah E. M. Howie

  • Series Title: Molecular Biology Intelligence Unit

  • DOI: https://doi.org/10.1007/978-0-387-39957-7

  • Publisher: Springer New York, NY

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Springer-Verlag New York 2007

  • Hardcover ISBN: 978-0-387-39956-0Published: 12 October 2006

  • Softcover ISBN: 978-1-4419-2294-6Published: 05 January 2011

  • eBook ISBN: 978-0-387-39957-7Published: 24 May 2008

  • Series ISSN: 1431-0414

  • Edition Number: 1

  • Number of Pages: XI, 158

  • Number of Illustrations: 36 b/w illustrations, 4 illustrations in colour

  • Additional Information: Jointly published with Landes Bioscience, Austin, TX, USA

  • Topics: Developmental Biology, Cell Biology, Human Physiology

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