Molecular Biology Intelligence Unit

Shh and Gli Signalling in Development

Editors: Howie, Sarah, Fisher, Carolyn Elaine (Eds.)

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eBook $169.00
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  • ISBN 978-0-387-39957-7
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Hardcover $219.99
price for USA in USD
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About this book

he hedgehog signalling pathway is highly conserved and seen in organisms ranging from Drosophila to humans. This pathway is Tcritical in determining cell fate decisions in a variety of different cell types. There are several vertebrate analogues of the Drosophila hedgehog protein of which the most widely studied is Sonic hedgehog (Shh). Shh signalling classically involves the Gli family of zinc-fmger transcription factors. The Shh signalling pathway is well characterised in the develop­ ment of a number of vertebrate organ systems. It could indeed be argued that the Shh and Gli signalling may well be involved at some stage in the development of all the major organ systems in vertebrates. This volume rep­ resents a concerted drive to bring together *state of the art' reviews by lead­ ing experts in the field of Shh and Gli signalling in development from all over the world. The chapters span vertebrate organisms from zebrafish to humans and cover development of the multiple organ systems in which the Shh signalling pathway is crucial for normal development. There are chap­ ters on the development of the central nervous system, skeletal struc­ tures, visceral organs, prostate, lung, immune system and the structures of the human face. The authors themselves span three major continents and multiple nationalities which admirably illustrates the worldwide nature of the science.

Table of contents (14 chapters)

  • Introduction

    Fisher, Carolyn E. (et al.)

    Pages 1-11

  • Sonic Hedgehog Signalling in Dorsal Midline and Neural Development

    López, Silvia L. (et al.)

    Pages 12-22

  • Role of Hedgehog and Gli Signalling in Telencephalic Development

    Zaki, Paulette A. (et al.)

    Pages 23-35

  • Role of Shh and Gli Signalling in Oligodendroglial Development

    Tan, Min (et al.)

    Pages 36-43

  • The Role of Sonic Hedgehog Signalling in Craniofacial Development

    Cordero, Dwight (et al.)

    Pages 44-57

Buy this book

eBook $169.00
price for USA in USD (gross)
  • ISBN 978-0-387-39957-7
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $219.99
price for USA in USD
  • ISBN 978-0-387-39956-0
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $219.99
price for USA in USD
  • ISBN 978-1-4419-2294-6
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Shh and Gli Signalling in Development
Editors
  • Sarah Howie
  • Carolyn Elaine Fisher
Series Title
Molecular Biology Intelligence Unit
Copyright
2007
Publisher
Springer-Verlag New York
Copyright Holder
Springer-Verlag New York
eBook ISBN
978-0-387-39957-7
DOI
10.1007/978-0-387-39957-7
Hardcover ISBN
978-0-387-39956-0
Softcover ISBN
978-1-4419-2294-6
Series ISSN
1431-0414
Edition Number
1
Number of Pages
XI, 158
Number of Illustrations and Tables
36 b/w illustrations, 4 illustrations in colour
Additional Information
Jointly published with Landes Bioscience, Austin, TX, USA
Topics