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Handbook of Neurochemistry and Molecular Neurobiology

Development and Aging Changes in the Nervous System

  • Reference work
  • © 2008

Overview

  • Addresses sampling of major elements of neural function at the cellular and molecular level that play important roles in development and aging

  • Stresses the dynamic features of neuronal responses to internal (developmental) cues and the more harmful external events (injury and disease)

  • Topics include neurotrophins, oligodendroglia, myelination, stress response, plasticity, misfolding proteins, and interventions to counteract aging-associated illness

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Table of contents (13 entries)

About this book

In the animal nervous system, a very high metabolic turnover, fragile but steep ionic gradients, and morphological and structural constraints - dictated by the necessity for prompt neuronal transmission of electrical impulses and necessary plasticity - result in a highly fragile organ system. Here, we address a small sampling of major constituents of neural function at the cellular and molecular level that play important roles in development and aging, two endogenous processes that embody features of allostasis or the dynamic shifts in set points for specific homeostatic mechanisms associated with development and aging. These chapters stress the dynamic features of neuronal responses to internal (developmental) cues or the more harmful external events (injury and disease) in a modern perspective.

Editors and Affiliations

  • Center for Neurochemistry, Nathan S. Kline Institute for Psychiatric Research, New York, USA

    Abel Lajtha

  • Department of Biochemistry & Molecular Biology, University of Texas Medical Branch, Galveston, USA

    J. Regino Perez-Polo

  • Universität Leipzig Medizinische Fakultät, Paul-Flechsig-Institut für Hirnforschung, Leipzig, Germany

    Steffen Rossner

Bibliographic Information

  • Book Title: Handbook of Neurochemistry and Molecular Neurobiology

  • Book Subtitle: Development and Aging Changes in the Nervous System

  • Editors: Abel Lajtha, J. Regino Perez-Polo, Steffen Rossner

  • DOI: https://doi.org/10.1007/978-0-387-32671-9

  • Publisher: Springer New York, NY

  • eBook Packages: Biomedical and Life Sciences, Reference Module Biomedical and Life Sciences

  • Copyright Information: Springer-Verlag US 2008

  • Hardcover ISBN: 978-0-387-32670-2Published: 06 June 2008

  • eBook ISBN: 978-0-387-32671-9Published: 23 February 2010

  • Edition Number: 3

  • Number of Pages: X, 324

  • Number of Illustrations: 48 b/w illustrations

  • Topics: Neurosciences

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