Advances in Experimental Medicine and Biology

Polyomaviruses and Human Diseases

Editors: Ahsan, Nasimul (Ed.)

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  • ISBN 978-0-387-32957-4
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Hardcover $279.99
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  • ISBN 978-0-387-29233-5
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  • ISBN 978-1-4419-2122-2
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About this book

Science never solves apr oblem without creating ten more Geor ge Bernard Shaw How prophetic the above words prove to be when applied to the advances of 20th century medicine. Prior to Banting and Best, chnicians were unaware of the ravages of diabetes, patients simply wasted away and died. Following the purifica­ tion of insulin, clinicians now had to deal with diabetic retinopathy, diabetic neph­ ropathy and all the other complications of long-term diabetes. A little over 50 years ago, the first successful human kidney transplant was performed in Boston. The first 30 years of the experience had successes when compared to the alternative but were a constant struggle to get even 50% of the grafts from deceased donors to survive more than a year. However, the science continued to advance knowledge of the immune response. With this came more and increasingly powerful tools for the clinician. Suddenly, success rates of 80-90% at one year were attainable. With this success came new problems, new complications and clinicians now had to worry about the long-term consequences of their therapy as patients were surviving with functional grafts for extended periods. A particular infectious complication evolved with the application of ever more powerful immunosuppressant drugs. Astute clinicians noted that occasionally cellular rejections seemed to get worse with steroids. Despite their best efforts and the use of powerful drugs, patients lost their grafts to overwhelming interstitial infiltrates not seen before.

Table of contents (24 chapters)

Table of contents (24 chapters)

Buy this book

eBook $219.00
price for USA in USD (gross)
  • ISBN 978-0-387-32957-4
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $279.99
price for USA in USD
  • ISBN 978-0-387-29233-5
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $279.99
price for USA in USD
  • ISBN 978-1-4419-2122-2
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Polyomaviruses and Human Diseases
Editors
  • Nasimul Ahsan
Series Title
Advances in Experimental Medicine and Biology
Series Volume
577
Copyright
2006
Publisher
Springer-Verlag New York
Copyright Holder
Springer-Verlag New York
eBook ISBN
978-0-387-32957-4
DOI
10.1007/0-387-32957-9
Hardcover ISBN
978-0-387-29233-5
Softcover ISBN
978-1-4419-2122-2
Series ISSN
0065-2598
Edition Number
1
Number of Pages
XXIV, 360
Number of Illustrations
60 b/w illustrations, 19 illustrations in colour
Topics