Overview
This is the only title on experimental models of multiple sclerosis
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Table of contents (51 chapters)
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Front Matter
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Experimental Allergic (Autoimmune) Encephalomyelitis (EAE)
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Front Matter
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Keywords
About this book
Multiple Sclerosis (MS) is an enigmatic immune mediated disease of the central nervous system that affects about 350,000 individuals in the US, and many more around the world. The mechanism of this disease is largely unknown and there is no cure for it. However, there are several well-characterized experimental animal models that help us understand and speculate about potential mechanisms of pathology in this disease. Many of the experimental therapies designed for this disease rely on testing the drugs in animal models before using it in clinical trials. This book combines for the first time the different experimental models for MS (including immune-mediated and viral) under one roof, and highlights aspects that are different or shared among these experimental models. It’s aim is to improve our understanding of this devastating disease and help us think about potential additional therapies for it.
Reviews
From the reviews:
"A specialist book that aims to combine and present information about every existing animal model for multiple sclerosis. The target audience for this book includes neuroscientists, neurologists, immunologists, microbiologists, and neuropathologists. Clearly, some neuroradiologists … will also benefit from the information in this book. For the readers of AJNR, it is thought that a primary use of this book might be a reference for those collaborating with basic neuroscientists. … This will be a valuable resource for any scientists … ." (American Journal of Neuroradiology, January, 2007)
Editors and Affiliations
Bibliographic Information
Book Title: Experimental Models of Multiple Sclerosis
Editors: Ehud Lavi, Cris S. Constantinescu
DOI: https://doi.org/10.1007/b135502
Publisher: Springer New York, NY
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: Springer-Verlag US 2005
Hardcover ISBN: 978-0-387-25517-0Published: 29 November 2005
eBook ISBN: 978-0-387-25518-7Published: 03 January 2008
Edition Number: 1
Number of Pages: XIV, 902
Topics: Immunology, Virology, Neurosciences, Pathology, Neurology