Metabolome Analyses:

Strategies for Systems Biology

Editors: Vaidyanathan, Seetharaman, Harrigan, George G., Goodacre, Royston (Eds.)

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Hardcover $249.99
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Softcover $199.99
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About this book

Metabolome Analyses is intended as a follow-up to Metabolic Profiling: Its Role in Biomarker Discovery and Gene Function Analysis (Kluwer, 2003). That text offered guidelines to currently available technology, bioinformatics and databases. Evidence was presented showing metabolic profiling as a valuable addition to genomics and proteomics strategies devoted to drug discovery and development. This book focuses on how metabolic profiling is being more comprehensively integrated with the other "omics" technologies. It provides more practical applications of such "panomics" or "Systems Biology" approaches. The expanding use of mass spectrometry as a measurement technology in metabolic profiling is addressed through demonstrated applications. The integration of metabolic profiling and proteomics is probably most developed for plant-based studies, which was not addressed in Volume 1. Other areas related to metabolic profiling continue to show significant development. These include database strategies and an increased acceptance by the pharmaceutical industry of metabolic profiling. Also covered is the use of in silico metabolic networks. Again the focus is primarily on the pharmaceutical industry but the importance of metabolic profiling to studies on human nutrition (a burgeoning area) is discussed.

The primary audience for Metabolome Analyses consists of academics (professors, post-doctoral researchers) involved in metabolic analyses, genomics transcriptomics, proteomics, bioinformatics; and corresponding researchers in the pharmaceutical and biotechnology industries (including Big Pharma, mid –capital and small venture-capital based enterprises) and in research institutes.

Table of contents (21 chapters)

  • Introduction

    Vaidyanathan, Seetharaman (et al.)

    Pages 1-7

  • Towards Integrative Functional Genomics Using Yeast as a Reference Model

    Castrillo, Juan I. (et al.)

    Pages 9-29

  • Metabolomics for the Assessment of Functional Diversity and Quality Traits in Plants

    Hall, Robert D. (et al.)

    Pages 31-44

  • Metabolomics: A New Approach Towards Identifying Biomarkers and Therapeutic Targets in CNS Disorders

    Kaddurah-Daouk, Rima (et al.)

    Pages 45-61

  • Comparative Metabolome Profiling Using Two Dimensional Thin Layer Chromatography (2DTLC)

    Ferenci, Thomas (et al.)

    Pages 63-81

Buy this book

eBook $149.00
price for USA in USD (gross)
  • ISBN 978-0-387-25240-7
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $249.99
price for USA in USD
  • ISBN 978-0-387-25239-1
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $199.99
price for USA in USD
  • ISBN 978-1-4419-3780-3
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Metabolome Analyses:
Book Subtitle
Strategies for Systems Biology
Editors
  • Seetharaman Vaidyanathan
  • George G. Harrigan
  • Royston Goodacre
Copyright
2005
Publisher
Springer US
Copyright Holder
Springer-Verlag US
eBook ISBN
978-0-387-25240-7
DOI
10.1007/b106967
Hardcover ISBN
978-0-387-25239-1
Softcover ISBN
978-1-4419-3780-3
Edition Number
1
Number of Pages
XXII, 390
Topics