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  • Conference proceedings
  • © 2005

Chemistry and Safety of Acrylamide in Food

  • Acrylamide in food is currently a very hot topic. It has been discussed at the Institute of Food Technologists
  • The formation of potential carcinogens and neurotoxins in everyday food is clearly very important, and members of the agriculture and food industry need to be aware of the latest developments on this topic
  • A proceedings from a conference on acrylamide fills this void

Part of the book series: Advances in Experimental Medicine and Biology (AEMB, volume 561)

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Table of contents (34 papers)

  1. Front Matter

    Pages i-xi
  2. Acrylamide in Food: The Discovery and Its Implications

    • Margareta Törnqvist
    Pages 1-19
  3. Mechanisms of Acrylamide Induced Rodent Carcinogenesis

    • James E. Klaunig, Lisa M. Kamendulis
    Pages 49-62
  4. Exposure to Acrylamide

    • Barbara J. Petersen, Nga Tran
    Pages 63-76
  5. Acrylamide and Glycidamide: Approach towards Risk Assessment Based on Biomarker Guided Dosimetry of Genotoxic/Mutagenic Effects in Human Blood

    • Matthias Baum, Evelyne Fauth, Silke Fritzen, Armin Herrmann, Peter Mertes, Melanie Rudolphi et al.
    Pages 77-88
  6. Pilot Study on the Impact of Potato Chips Consumption on Biomarkers of Acrylamide Exposure

    • Hubert W. Vesper, Hermes Licea-Perez, Tunde Meyers, Maria Ospina, Gary L. Myers
    Pages 89-96
  7. LC/MS/MS Method for the Analysis of Acrylamide and Glycidamide Hemoglobin Adducts

    • Maria Ospina, Hubert W. Vesper, Hermes Licea-Perez, Tunde Meyers, Luchuan Mi, Gary Myers
    Pages 97-107
  8. Comparison of Acrylamide Metabolism in Humans and Rodents

    • Timothy R. Fennell, Marvin A. Friedman
    Pages 109-116
  9. In Vitro Studies of the Influence of Certain Enzymes on the Detoxification of Acrylamide and Glycidamide in Blood

    • Birgit Paulsson, Margareta Warholm, Agneta Rannug, Margareta Törnqvist
    Pages 127-133
  10. Mechanisms of Acrylamide Formation

    • I. Blank, F. Robert, T. Goldmann, P. Pollien, N. Varga, S. Devaud et al.
    Pages 171-189
  11. Mechanistic Pathways of Formation of Acrylamide from Different Amino Acids

    • Varoujan A. Yaylayan, Carolina Perez Locas, Andrzej Wnorowski, John O’Brien
    Pages 191-203
  12. New Aspects on the Formation and Analysis of Acrylamide

    • Peter Schieberle, Peter Köhler, Michael Granvogl
    Pages 205-222
  13. Formation of Acrylamide from Lipids

    • Stefan Ehling, Matt Hengel, Takayuki Shibamoto
    Pages 223-233
  14. Kinetic Models as a Route to Control Acrylamide Formation in Food

    • Bronislaw L. Wedzicha, Donald S. Mottram, J. Stephen Elmore, Georgios Koutsidis, Andrew T. Dodson
    Pages 235-253
  15. The Effect of Cooking on Acrylamide and Its Precursors in Potato, Wheat and Rye

    • J. Stephen Elmore, Georgios Koutsidis, Andrew T. Dodson, Donald S. Mottram, Bronislaw L. Wedzicha
    Pages 255-269

About this book

Reports that heat processing of foods induces the formation of acrylamide heightened interest in the chemistry, biochemistry, and safety of this compound. Acrylamide-induced neurotoxicity, reproductive toxicity, genotoxicity, and carcinogenicity are potential human health risks based on animal studies. Because exposure of humans to acrylamide can come from both external sources and the diet, there exists a need to develop a better understanding of its formation and distribution in food and its role in human health. To contribute to this effort, experts from eight countries have presented data on the chemistry, analysis, metabolism, pharmacology, and toxicology of acrylamide.

Specifically covered are the following aspects: exposure from the environment and the diet; biomarkers of exposure; risk assessment; epidemiology; mechanism of formation in food; biological alkylation of amino acids, peptides, proteins, and DNA by acrylamide and its epoxide metabolite glycidamide; neurotoxicity, reproductive toxicity, and carcinogenicity; protection against adverse effects; and possible approaches to reducing levels in food. Cross-fertilization of ideas among several disciplines in which an interest in acrylamide has developed, including food science, pharmacology, toxicology, and medicine, will provide a better understanding of the chemistry and biology of acrylamide in food, and can lead to the development of food processes to decrease the acrylamide content of the diet.

Reviews

From the reviews:

"Exposure of humans to acrylamide cannot only come from external sources … but also from the diet. This new aspect initiates researchers to develop a better understanding of its formation … . a Symposium … took place in Anaheim, California on March 29-31, 2004. … The Proceedings of this symposium have been published in the Series ‘Advances in Experimental Medicine and Biology’ … . this volume is recommended to all researchers and professionals in the field of food science. They must have it … ." (Advances in Food Sciences, Vol. 28 (1), 2006)

Editors and Affiliations

  • Agricultural Research Service, USDA, Albany

    Mendel Friedman

  • University of Reading, Reading, UK

    Don Mottram

Bibliographic Information

  • Book Title: Chemistry and Safety of Acrylamide in Food

  • Editors: Mendel Friedman, Don Mottram

  • Series Title: Advances in Experimental Medicine and Biology

  • DOI: https://doi.org/10.1007/b106417

  • Publisher: Springer New York, NY

  • eBook Packages: Chemistry and Materials Science, Chemistry and Material Science (R0)

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Business Media, LLC, part of Springer Nature 2005

  • Hardcover ISBN: 978-0-387-23920-0Published: 22 April 2005

  • Softcover ISBN: 978-1-4419-3672-1Published: 11 August 2011

  • eBook ISBN: 978-0-387-24980-3Published: 18 July 2006

  • Series ISSN: 0065-2598

  • Series E-ISSN: 2214-8019

  • Edition Number: 1

  • Number of Pages: XII, 466

  • Number of Illustrations: 147 b/w illustrations

  • Topics: Food Science, Chemistry/Food Science, general

Buy it now

Buying options

eBook USD 169.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 219.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 219.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access