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Cancer Treatment and Research

Selective Sentinel Lymphadenectomy for Human Solid Cancer

Editors: Leong, Stanley P. L., Kitagawa, Yuko, Kitajima, Masaki (Eds.)

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Hardcover $159.99
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  • ISBN 978-0-387-23603-2
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  • ISBN 978-1-4899-8869-0
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About this book

Lymph node (LN) status is the most important prognostic indicator for the clinical outcome of patients in human solid cancer. Recent developments in sentinel lymph node (SLN) concept and technology have resulted in the application of this revolutionary approach to determine if cancer has metastasized. The underlying thesis in solid cancer biology is that metastasis generally starts in an orderly progression, often spreading through the lymphatic channels to the SLN. Thus, the logical approach is to harvest that specific SLN for thorough analysis.

The most exciting possibility of selective sentinel lymphadenectomy (SSL) is that it will lead to early diagnosis of micrometastasis in regional LNs. Early diagnosis makes it useful as a clinical staging procedure, and opens up new opportunities to study micrometastasis and its evolution within the SLNs.

New molecular and genetic tools may be used to dissect the mechanisms of lymphatic and hemotogenous routes of metastasis. If such mechanisms can be understood, new therapeutic advances may be developed to prevent the process of micrometastasis.

***********************************************************************************

Minimally invasive surgery associated with reduced morbidity has transformed the management of cancer patients. Sentinel lymphadenectomy for staging and treatment of solid tumors is now standard of care in many settings. In this text, distinguished investigators review the technical aspects and clinical considerations related to this procedure.

Steven T. Rosen, M.D.
Series Editor

Reviews

From the reviews:

"This is a current comprehensive book on sentinel lymphadenectomy … . The book is written for the surgeon … . This includes residents in training, surgical oncology fellows, and practicing surgeons. The written detail, supporting diagrams, and pictures provide a complete practice manual. … A single book that contains 10 years of journal material is convenient and for those not following the literature invaluable. … no other book has united several different diseases and explored them through the SLN concept." (Neal Wilkinson, Doody's Electronic Journal, May, 2005)


Table of contents (14 chapters)

  • The Development of Lymphatic Mapping and Selective Lymphadenectomy

    Wong, Jan H.

    Pages 1-14

  • Role of Lymphoscintigraphy for Selective Sentinel Lymphadenectomy

    Uren, Roger F. (et al.)

    Pages 15-38

  • Selective Sentinel Lymphadenectomy for Malignant Melanoma, Merkel Cell Carcinoma, and Squamous Cell Carcinoma

    Leong, Stanley P. L.

    Pages 39-76

  • Selective Sentinel Lymphadenectomy for Breast Cancer

    Cox, Charles E. (et al.)

    Pages 77-104

  • Sentinel Lymph Node Mapping in Colon and Rectal Cancer

    Saha, Sukamal (et al.)

    Pages 105-122

Buy this book

eBook $119.00
price for USA in USD (gross)
  • ISBN 978-0-387-23604-9
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $159.99
price for USA in USD
  • ISBN 978-0-387-23603-2
  • book with DVD
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $159.99
price for USA in USD
  • ISBN 978-1-4899-8869-0
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Selective Sentinel Lymphadenectomy for Human Solid Cancer
Editors
  • Stanley P. L. Leong
  • Yuko Kitagawa
  • Masaki Kitajima
Series Title
Cancer Treatment and Research
Series Volume
127
Copyright
2005
Publisher
Springer US
Copyright Holder
Springer-Verlag US
eBook ISBN
978-0-387-23604-9
DOI
10.1007/b101891
Hardcover ISBN
978-0-387-23603-2
Softcover ISBN
978-1-4899-8869-0
Series ISSN
0927-3042
Edition Number
1
Number of Pages
XXIII, 297
Topics