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Statistics for Biology and Health

Statistical Genetics of Quantitative Traits

Linkage, Maps and QTL

Authors: Wu, Rongling, Ma, Changxing, Casella, George

  • Includes a detailed description of a number of statistical approaches and the step-by-step demonstration of live-example analyses designed to explain the utilization and usefulness of statistical methods
  • The book contains exercise sets and computer codes for all the analyses used, giving graduates and senior undergraduates a deeper understanding of the methodology
  • Provides statistical models and analytical procedures for detecting specific genes, enabling readers to use the book as a practical tool
  • Concentrates on the linkage analysis of markers, map construction and quantitative trait locus (QTL) mapping
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eBook $139.00
price for USA in USD (gross)
  • ISBN 978-0-387-68154-2
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $249.99
price for USA in USD
  • ISBN 978-0-387-20334-8
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $179.99
price for USA in USD
  • ISBN 978-1-4419-1912-0
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

The book introduces the basic concepts and methods that are useful in the statistical analysis and modeling of DNA-based marker and phenotypic data that arise in agriculture, forrestry, experimental biology, and other fields. It concentrates on the linkage analysis of markers, map construction and quantitative trait locus (QTL) mapping and assumes a background in regression analysis and maximum likelihood approaches. The strengths of this book lie in the construction of general models and algorithms for linkage analysis and QTL mapping in any kind of crossed pedigrees initiated with inbred lines of crops and plant and animal model systems or outbred lines in forest trees and wildlife species.

The book includes a detailed description of each approach and the step-by-step demonstration of live-example analyses designed to explain the utilization and usefulness of statistical methods. The book also includes exercise sets and computer codes for all the analyses used.

This book can serve as a textbook for graduates and senior undergraduates in genetics, agronomy, forest biology, plant breeding and animal sciences. It will also be useful to researchers and other professionals in the areas of statistics, biology and agriculture.

Rongling Wu is Associate Professor of Statistics at the University of Florida, Gainesville. He currently serves as Associate Editor for six genetics and bioinformatics journals. Chang-Xing Ma is Assistant Professor of Biostatistics at the State University of New York at Buffalo. George Casella is Distinguished Professor of Statistics and Distinguished Member of the Genetics Institute at the Univesity of Florida, Gainesville. He is a fellow of the American Statistical Association and the Institute of Mathematical Sciences, and the author of four other statistics books.

Reviews

From the Reviews:

"[I]t is a big help and guidance in the field of statistical developments for genetic mapping, synthesised all in one volume helping to build a bridge between genetics and statistics." (Lutz Bunger, Genetic Research, 89, 2007)

"...[T]his is an ideal book for a young researcher looking for an exciting and developing field to get into." (International Statistics Review, April 2008)


Table of contents (14 chapters)

Buy this book

eBook $139.00
price for USA in USD (gross)
  • ISBN 978-0-387-68154-2
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $249.99
price for USA in USD
  • ISBN 978-0-387-20334-8
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $179.99
price for USA in USD
  • ISBN 978-1-4419-1912-0
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Statistical Genetics of Quantitative Traits
Book Subtitle
Linkage, Maps and QTL
Authors
Series Title
Statistics for Biology and Health
Copyright
2007
Publisher
Springer-Verlag New York
Copyright Holder
Springer-Verlag New York
eBook ISBN
978-0-387-68154-2
DOI
10.1007/978-0-387-68154-2
Hardcover ISBN
978-0-387-20334-8
Softcover ISBN
978-1-4419-1912-0
Series ISSN
1431-8776
Edition Number
1
Number of Pages
XVI, 368
Topics