Nanobioelectronics - for Electronics, Biology, and Medicine

1. Front Matter

   Pages i-xiv

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2. DNA-Based Nanobioelectronics

   1. Front Matter

      Pages 5-8

      PDF

3. Introduction

   1. Introduction

      • Andreas Offenhäusser, Ross Rinaldi

      Pages 1-3

4. DNA-Based Nanobioelectronics

   1. Front Matter

      Pages 5-8

      PDF

   2. DNA for Electronics

      1. DNA-Mediated Assembly of Metal Nanoparticles: Fabrication, Structural Features, and Electrical Properties

         • Monika Fischler, Melanie Homberger, Ulrich Simon

         Pages 11-41

      2. DNA-Based Nanoelectronics

         • Rosa Di Felice

         Pages 43-79

   3. Electronics for Genomics

      1. DNA Detection with Metallic Nanoparticles

         • Robert Möller, Grit Festag, Wolfgang Fritzsche

         Pages 82-101

      2. Label-Free, Fully Electronic Detection of DNA with a Field-Effect Transistor Array

         • Sven Ingebrandt, Andreas Offenhäusser

         Pages 103-129

5. Protein-Based Nanobioelectronics

   1. Front Matter

      Pages 131-135

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   2. Protein-Based Nanoelectronics

      1. Nanoelectronic Devices Based on Proteins

         • Giuseppe Maruccio, Alessandro Bramanti

         Pages 139-166

      2. S-Layer Proteins for Assembling Ordered Nanoparticle Arrays

         • Dietmar Pum, Uwe B. Sleytr

         Pages 167-180

   3. Electronics for Proteomics

      1. Electrochemical Biosensing of Redox Proteins and Enzymes

         • Qijin Chi, Palle S. Jensen, Jens Ulstrup

         Pages 182-209

      2. Ion Channels in Tethered Bilayer Lipid Membranes on Au Electrodes

         • Ingo Köper, Inga K. Vockenroth, Wolfgang Knoll

         Pages 211-223

      3. Fluorescent Nanocrystals and Proteins

         • Pier Paolo Pompa, Teresa Pellegrino, Liberato Manna

         Pages 225-254

6. Cell-Based Nanobioelectronics

   1. Front Matter

      Pages 255-257

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   2. Neuron-Based Information Processing

      1. Spontaneous and Synchronous Firing Activity in Solitary Microcultures of Cortical Neurons on Chemically Patterned Multielectrode Arrays

         • T. G. Ruardij, W. L. C. Rutten, G. van Staveren, B. H. Roelofsen

         Pages 261-275

      2. Nanomaterials for Neural Interfaces: Emerging New Function and Potential Applications

         • Allison J. Beattie, Adam S. G. Curtis, Chris D. W. Wilkinson, Mathis Riehle

         Pages 277-286

      3. Interfacing Neurons and Silicon-Based Devices

         • Andreas Offenhäusser, Sven Ingebrandt, Michael Pabst, Günter Wrobel

         Pages 287-301

   3. Electronics for Cellomics

      1. Hybrid Nanoparticles for Cellular Applications

         • Franco Calabi

         Pages 304-330

7. Back Matter

   Pages 331-337

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The combination of biological elements with electronics is of great interest for many research areas. Inspired by biological signal processes, scientists and engineers are exploring ways of manipulating, assembling, and applying biomolecules and cells on integrated circuits, joining biology with electronic devices. The overall goal is to create bioelectronic devices for biosensing, drug discovery, and curing diseases, but also to build new electronic systems based on biologically inspired concepts. This research area called bioelectronics requires a broad interdisciplinary and transdisciplinary approach to biology and material science. Even though at the frontier of life science and material science, bioelectronics has achieved in the last years many objectives of scientific and industrial relevance, including aspects of electronics and biotechnology. Although the first steps in this field combined biological and electronic units for sensor applications (e. g. , glucose oxidase on an oxygen electrode), we see now many applications in the fields of genomics, proteomics, and celomics as well as electronics. This approach challenges both the researcher and the student to learn and think outside of their zones of comfort and training. Today, one can fabricate electrically active structures that are commensurate in size with biomolecules. The advancement of nanotechnology has influenced bioelectronics to a large extent.

• Biosensor
• DNA
• Lipid
• Potential
• Sensor
• biosensing
• electronics
• enzymes
• fabrication
• information processing
• nanomaterial
• network
• protein
• proteins
• transistor
• biochemical engineering

• Institute of Bio- and Nanosystems, Forschungszentrum Jülich, Jülich, Germany

  Andreas Offenhäusser

• CNR Lecce, Ist. Nazionale di Fisica della Materia, National Nanotechnology Lab. (NNL), Lecce, Italy

  Ross Rinaldi

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