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Antibodies

Volume 2: Novel Technologies and Therapeutic Use

Editors: Subramanian, G. (Ed.)

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  • ISBN 978-1-4419-8877-5
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Hardcover $179.99
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  • ISBN 978-0-306-48315-8
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Softcover $169.99
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  • ISBN 978-1-4613-4702-6
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About this book

It is now over one hundred years since von Behring and Kitsato first concluded experiments that led to the use of passive immunisation, employing antibodies raised in animals against tetanus and diphtheria toxins. The advancement of technology both in manufacturing purity product in a cost effective way and the clinical research has proved that antibodies are one ofthe most successful products in biotechnology. Monoclonal antibodies account for between one-third and one-halfof all pharmaceutical products in development and human clinical trials. Both the nature of monoclonal antibody therapies and the relatively large size of the monoclonal antibody dictate the production requirements, for many ofthese therapeutics the monoclonal antibody product will be 100 kilogrammes or more per year. It is widely acknowledged that there is currently a worldwide shortage of biomanufacturing capacity, and the active pharmaceutical ingredient material requirements for these products are expected to increase. Thus the industry is looking for new sources and extensive studies are being carried out not only for alternative technology to meet the needs but also to reveal the new therapeutic applicationsofantibodies. This book brings to the forefront current advances in novel technologies for the manufacturing of monoclonal antibodies and also their extensive clinical importance. The first four chapters give an overview of the new technologies and the successful application in the manufacture of monoclonal antibodies with clinical purity. The next chapters address the application of antibodies in cancer therapy and functional genomic therapy.

Table of contents (12 chapters)

Table of contents (12 chapters)
  • Transgenic Technology for Monoclonal Antibody Production

    Pages 1-11

    Sensoli, Steve

  • Generation, Engineering and Production of Human Antibodies Using Hucal®

    Pages 13-52

    Ostendorp, Ralf (et al.)

  • Achieving Appropriate Glycosylation During the Scaleup of Antibody Production

    Pages 53-78

    Deng, X. K. (et al.)

  • Approaches to Devise Antibody Purification Processes by Chromatography

    Pages 79-103

    Boschetti, Egisto

  • Novel Hiv Neutralizing Antibodies Selected from Phage Display Libraries

    Pages 105-117

    Moulard, Maxime (et al.)

Buy this book

eBook $129.00
price for USA in USD
  • ISBN 978-1-4419-8877-5
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $179.99
price for USA in USD
  • ISBN 978-0-306-48315-8
  • Free shipping for individuals worldwide
  • Institutional customers should get in touch with their account manager
  • Covid-19 shipping restrictions
  • Usually ready to be dispatched within 3 to 5 business days, if in stock
Softcover $169.99
price for USA in USD
  • ISBN 978-1-4613-4702-6
  • Free shipping for individuals worldwide
  • Institutional customers should get in touch with their account manager
  • Covid-19 shipping restrictions
  • Usually ready to be dispatched within 3 to 5 business days, if in stock
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Bibliographic Information

Bibliographic Information
Book Title
Antibodies
Book Subtitle
Volume 2: Novel Technologies and Therapeutic Use
Editors
  • G. Subramanian
Copyright
2004
Publisher
Springer US
Copyright Holder
Springer Science+Business Media New York
eBook ISBN
978-1-4419-8877-5
DOI
10.1007/978-1-4419-8877-5
Hardcover ISBN
978-0-306-48315-8
Softcover ISBN
978-1-4613-4702-6
Edition Number
1
Number of Pages
XVI, 232
Topics