Advances in Experimental Medicine and Biology

Dipeptidyl Aminopeptidases in Health and Disease

Editors: Hildebrandt, M., Klapp, B., Hoffmann, T., Demuth, H.-U. (Eds.)

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About this book

Proceedings of the International Conference on Dipeptidyl Aminopeptidases, held September 26-28, 2002, in Berlin, Germany.

Dipeptidyl Aminopeptidases exert a potent modulatory role at an interface between immune mechanisms, metabolic responses and neuroendocrine pathways. Experimental models and clinical studies addressing the role of these enzymes and the effect of specific inhibitors pave the way to novel therapeutic concepts in immunology, rheumatology, oncology, reproductive medicine and diabetes.

Leading experts in this field have contributed to this book which presents a state-of-the-art view on these enzymes, at a time when our understanding of their function is growing ever more rapidly and therapeutic options become imminent. The sections of the book focus on various topics:

- Structure and function of dipeptidyl aminopeptidases,
- DPP IV-like proteins,
- Immune mechanisms and immune disorders,
- Cancer and angiogenesis,
- Diabetes and metabolism,
- Therapeutic implications.

Table of contents (42 chapters)

Table of contents (42 chapters)
  • Dipeptidyl Peptidase IV Substrates

    Meester, Ingrid (et al.)

    Pages 3-17

  • Structure-Function Relationship of DPP IV: Insights into its Dimerisation and Gelatinase Activity

    Baum, Oliver (et al.)

    Pages 19-27

  • Exploration of the Active Site of Dipeptidyl Peptidase IV From Porphyromonas gingivalis

    Lambeir, Anne-Marie (et al.)

    Pages 29-35

  • Modification of the Biological Activity of Chemokines by Dipeptidyl Peptidase IV — a Side Effect in the Use of Inhibitors?

    Mentlein, Rolf (et al.)

    Pages 37-47

  • Molecular Chimeras and Mutational Analysis in the Prolyl Oligopeptidase Gene Family

    Ajami, Katerina (et al.)

    Pages 49-55

Buy this book

eBook $119.00
price for USA in USD (gross)
  • ISBN 978-0-306-47920-5
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $219.99
price for USA in USD
  • ISBN 978-0-306-47717-1
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $159.99
price for USA in USD
  • ISBN 978-1-4757-8730-6
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Dipeptidyl Aminopeptidases in Health and Disease
Editors
  • Martin Hildebrandt
  • Burghard Klapp
  • Torsten Hoffmann
  • Hans-Ulrich Demuth
Series Title
Advances in Experimental Medicine and Biology
Series Volume
524
Copyright
2003
Publisher
Springer US
Copyright Holder
Springer Science+Business Media New York
eBook ISBN
978-0-306-47920-5
DOI
10.1007/b105297
Hardcover ISBN
978-0-306-47717-1
Softcover ISBN
978-1-4757-8730-6
Series ISSN
0065-2598
Edition Number
1
Number of Pages
XXXII, 359
Number of Illustrations
72 b/w illustrations
Topics