Advances in Experimental Medicine and Biology

Neuroimmune Circuits, Drugs of Abuse, and Infectious Diseases

Editors: Friedman, Herman, Klein, Thomas W., Madden, John J. (Eds.)

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About this book

Introduction and Perspectives This volume is based on the proceedings of the 7th annual symposium on the topic Neuroimmune Circuits, Infectious Diseases and Drugs of Abuse, Bethesda, Maryland, Oc- ber 7–9, 1999. This symposium, as in the past, focused on newer knowledge concerning the relationship between the immune and nervous systems with regards to the effects of drugs of abuse and infections, including AIDS, caused by the immunodeficiency virus. Presentations discussed the brain-immune axis from the viewpoint of drugs of abuse rather than from the subject of the brain or immunity alone. The major aim of this series of conferences has been to clarify the consequences of immunomodulation induced by drugs of abuse in regards to susceptibility and pathogenesis of infectious diseases, both in man and in various animal model systems. The recreational use of drugs of abuse such as morphine, cocaine, and marijuana by large numbers of individuals in this country and around the world has continued to arouse serious concerns about the consequences of use of such drugs, especially on the normal physiological responses of an individual, including immune responses. Much of the recent data accumulated by investigators show that drugs of abuse, especially opioids and cannabinoids, markedly alter immune responses in human populations as well as in experimental animals, both in vivo and in vitro.

Table of contents (33 chapters)

Table of contents (33 chapters)
  • Targeting the Brain’s Immune System: A Psychopharmacological Approach to Central Nervous System Infections

    Peterson, Phillip K. (et al.)

    Pages 1-6

  • Model Systems for Assessing Cognitive Function: Implications for HIV-1 Infection and Drugs of Abuse

    Zink, Walter E. (et al.)

    Pages 7-27

  • Direct and Indirect Mechanisms of HIV-1 Neuropathogenesis in the Human Central Nervous System

    Hou, Jean (et al.)

    Pages 29-34

  • Chemokine Receptors on Brain Endothelia - Keys to HIV-1 Neuroinvasion?

    Fiala, Milan (et al.)

    Pages 35-40

  • Neurotrophic Factor Regulation of Human Immunodeficiency Virus Type 1 Replication in Human Blood-derived Macrophages Through Modulation of Coreceptor Expression

    Harrold, Sharon M. (et al.)

    Pages 41-47

Buy this book

eBook $129.00
price for USA in USD (gross)
  • ISBN 978-0-306-47611-2
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $219.99
price for USA in USD
  • ISBN 978-0-306-46466-9
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $169.99
price for USA in USD
  • ISBN 978-1-4757-8686-6
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Neuroimmune Circuits, Drugs of Abuse, and Infectious Diseases
Editors
  • Herman Friedman
  • Thomas W. Klein
  • John J. Madden
Series Title
Advances in Experimental Medicine and Biology
Series Volume
493
Copyright
2001
Publisher
Springer US
Copyright Holder
Springer Science+Business Media New York
eBook ISBN
978-0-306-47611-2
DOI
10.1007/b111373
Hardcover ISBN
978-0-306-46466-9
Softcover ISBN
978-1-4757-8686-6
Series ISSN
0065-2598
Edition Number
1
Number of Pages
X, 274
Topics