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Advances in Experimental Medicine and Biology

Cancer Gene Therapy

Past Achievements and Future Challenges

Editors: Habib, Nagy (Ed.)

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About this book

With the coming of the new millennium we are witnessing a revolution in our understanding of cancer genetics. These are very exciting times. Today we have at our disposal the technology to diagnose abnormalities in our cancer genes and the means to correct the deficit and very soon we will have the complete sequence of the human genome. With the use of gene chip technology the way doctors will be able to assess patients will change completely. Today we can diagnose abnormalities in ten thousand genes and within a short period of time we will be able to screen through our genome and discover potential abnormalities in our proto-oncogenes, tumour suppressor genes, differentiating genes, apoptotic genes and pro-inflammatory genes. In this book various authors have highlighted specific genes that could be expressed, overexpressed, neutralised or h- nessed to achieve cancer control. The problem of transferring the therapeutic gene into the cancer cell has been partly addressed with major developments in the field of naked plasmid DNA, adenovirus, retrovirus and adeno-associated viruses. However, further improvements are yet to be made to achieve significant gene transfer. Gene expression, in particular specificity of gene transfer, is obviously an important issue and one which is highlighted in this book by the use of specific promoter.

Table of contents (41 chapters)

Table of contents (41 chapters)

Buy this book

eBook $189.00
price for USA in USD (gross)
  • ISBN 978-0-306-46817-9
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $279.99
price for USA in USD
  • ISBN 978-0-306-46191-0
  • Free shipping for individuals worldwide
  • Immediate ebook access, if available*, with your print order
  • Usually dispatched within 3 to 5 business days.
Softcover $249.99
price for USA in USD
  • ISBN 978-1-4757-7370-5
  • Free shipping for individuals worldwide
  • Immediate ebook access, if available*, with your print order
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Cancer Gene Therapy
Book Subtitle
Past Achievements and Future Challenges
Editors
  • Nagy Habib
Series Title
Advances in Experimental Medicine and Biology
Series Volume
465
Copyright
2002
Publisher
Springer US
Copyright Holder
Springer Science+Business Media New York
eBook ISBN
978-0-306-46817-9
DOI
10.1007/b113267
Hardcover ISBN
978-0-306-46191-0
Softcover ISBN
978-1-4757-7370-5
Series ISSN
0065-2598
Edition Number
1
Number of Pages
XVI, 496
Topics

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