Advances in Experimental Medicine and Biology

Cytokines, Stress, and Depression

Editors: Dantzer, Robert, Wollmann, Emmanuelle E., Yirmiya, Raz (Eds.)

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About this book

Cytokines had been characterized in the early eighties as communication mole­ cules between immune cells, and between immunocytes and other peripheral cells, such as fibroblasts and endothelial cells. They play a key role in the regulation of the immune response and the coordination of the host response to infection. Based on these biological properties, nobody would have predicted that one decade later cytokines would burst upon neurosciences and permeate into several avenues of current research. In neurology, the connection between cytokines and inflammation, and the demonstration of a pivotal role of some of these molecules in cell death by apoptosis, prompted the investigation of their involvement in several neurological diseases involving an inflammatory component, including multiple sclerosis, brain trauma, stroke, and Alzheimer's disease. This movement started in the late eighties, and the corresponding field of research, known as neuroimmunology, is presently booming. In psychiatry, however, the relationship between cytokines and mental disorders was much less evident and took longer to materialize. The first indication that cytokines might be involved in psychopathology came from cancerology and internal medicine.

Table of contents (17 chapters)

Table of contents (17 chapters)

Buy this book

eBook $149.00
price for USA in USD (gross)
  • ISBN 978-0-585-37970-8
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $319.00
price for USA in USD
  • ISBN 978-0-306-46135-4
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $199.99
price for USA in USD
  • ISBN 978-1-4757-8610-1
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Cytokines, Stress, and Depression
Editors
  • Robert Dantzer
  • Emmanuelle E. Wollmann
  • Raz Yirmiya
Series Title
Advances in Experimental Medicine and Biology
Series Volume
461
Copyright
1999
Publisher
Springer US
Copyright Holder
Springer Science+Business Media New York
eBook ISBN
978-0-585-37970-8
DOI
10.1007/b102345
Hardcover ISBN
978-0-306-46135-4
Softcover ISBN
978-1-4757-8610-1
Series ISSN
0065-2598
Edition Number
1
Number of Pages
XII, 338
Topics