Erythrocytes as Drug Carriers in Medicine

Editors: Sprandel, Ulrich, Way, James L. (Eds.)

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About this book

The sixth meeting on the use of resealed annealed red blood cells was held in Irsee, Germany by the International Society for the Use of Resealed Erythrocytes (ISURE) on July 25-28, 1996. Although earlier meetings focused on the technology toward develop­ ment of methods and standardization for efficient, consistent encapsulation, most of the present studies now are directed toward the application use of these carrier blood cells. Basic studies now have been directed toward exploration of commercial applications. In­ deed, clinical trials were initiated to evaluate the dose-response curves employing L­ asparagenase in human patients. Also, studies have shown the use of thrombolytic agent in erythrocyte carriers with the use of human red blood cells to provide a new conceptual ap­ proach in thrombolytic therapy to prevent thrombosis in individuals with higher risk fac­ tors. For example, with the use of carrier red blood cells, the thrombolytic agents will have a greater potential of acting on clot formation without systemic activation and thus lower the risk of hemorrhage, which is always prevalent in the thrombolytic therapy.

Table of contents (19 chapters)

  • A Model for the Assessment of Human Recombinant Interleukin 2 (RIL2) Coated Erythrocytes as a Delivery System for Immunotherapy

    Moyes, R. B. (et al.)

    Pages 1-11

  • Human Recombinant Interleukin 2 Binds to Mouse Red Blood Cells via the Erythropoietin Receptor

    Moyes, Rita B. (et al.)

    Pages 13-23

  • In Vivo Survival of Human Energy-Replete Carrier Erythrocytes

    Bain, Murray D. (et al.)

    Pages 25-30

  • The Entrapment of Polyethylene Glycol-Conjugated Adenosine Deaminase (Pegademase) and Native Adenosine Deaminase in Human Carrier Erythrocytes

    Bax, Bridget E. (et al.)

    Pages 31-34

  • Use of Erythrocytes as a New Route of Administration of Fibrinolytic Agents

    Delahousse, Benedicte (et al.)

    Pages 35-42

Buy this book

eBook $149.00
price for USA in USD (gross)
  • ISBN 978-1-4899-0044-9
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $249.00
price for USA in USD
  • ISBN 978-0-306-45599-5
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $199.99
price for USA in USD
  • ISBN 978-1-4899-0046-3
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Erythrocytes as Drug Carriers in Medicine
Editors
  • Ulrich Sprandel
  • James L. Way
Copyright
1997
Publisher
Springer US
Copyright Holder
Springer Science+Business Media New York
eBook ISBN
978-1-4899-0044-9
DOI
10.1007/978-1-4899-0044-9
Hardcover ISBN
978-0-306-45599-5
Softcover ISBN
978-1-4899-0046-3
Edition Number
1
Number of Pages
VIII, 150
Topics