Calcium and Cellular Metabolism

1. Front Matter

   Pages i-viii

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2. Regulation of Calcium Signalling in Cells

   • Ernesto Carafoli

   Pages 1-15

3. Calcium Concentration Microdomains

   • Rodolfo Llinás, Mutsuyuki Sugimori, Robert Silver

   Pages 17-23

4. Rapid Confocal Measurements of Ca2+ Sparks in Rat Ventricular Myocytes

   • Lars Cleeman, Wei Wang, Martin Morad

   Pages 25-36

5. Calcium Channel Diversity at the Vertebrate Neuromuscular Junction

   • Osvaldo D. Uchitel, Eleonora Katz

   Pages 37-46

6. Comparison of the Effects of BDM on L-Type Ca Channels of Cardiac and Skeletal Muscle

   • Gonzalo Ferreira, Pablo Artigas, Rafael De Armas, Gonzalo Pizarro, Gustavo Brum

   Pages 47-57

7. Balls, Chains, and Potassium Channels

   • Ramón Latorre, Enrico Stefani, Ligia Toro

   Pages 59-71

8. The Plasma Membrane Calcium Pump

   • Ernesto Carafoli, Danilo Guerini

   Pages 73-84

9. The Concept of Phosphate Compounds of High and Low Energy

   • Leopoldo de Meis

   Pages 85-103

10. Understanding the Energy Source for Na+-Ca2+ Exchange after Dephosphorylation Steps of the Na+-ATPase Activity of Na+, K+-ATPase

    • Luis Beaugé, Marta Campos, Roberto Pezza

    Pages 105-116

11. Modulation of P-Glycoprotein on Tumour Cells

    • Monique Orind, Karen Wagner-Souza, Raquel C. Maia, Vivian M. Rumjanek

    Pages 117-124

12. Regulation of Neuronal Protein Synthesis by Calcium

    • J. R. Sotelo, J. M. Verdes, A. Kun, J. C. Benech, J. R. A. Sotelo Silveira, A. Calliari

    Pages 125-142

13. Local Protein Synthesis in the Squid Giant Axon and Presynaptic Terminals

    • Antonio Giuditta, Mariana Crispino, Carla Perrone Capano

    Pages 143-153

14. Protein Synthesis in Presynaptic Endings of Squid Brain: Regulation by Ca2+ Ions

    • Juan Claudio Benech, Mariana Crispino, Barry B. Kaplan, Antonio Giuditta

    Pages 155-162

15. Back Matter

    Pages 163-166

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When we began to organize the workshop "Calcium and Cellular Metabolism: Transport and Regulation" the goal we had in mind was to put together the knowledge of 2 several specialists on Ca + homeostasis, with various examples of cellular metabolisms 2 2 (such as protein synthesis), regulated by Ca + ions. Regarding the homeostasis of Ca + ions, we invited Ernesto Carafoli to write the first chapter as a general state-of-the-art introductory review. On the other hand, the other chapters are the contribution of different specialists on membrane calcium transport mechanisms, aiming to reunite at least in part the wide field of calcium homeostasis. We roughly try to group chapters that share similar subjects. The first group of chapters (Chapters 2 to 6), are mainly related to calcium channels. Thus, Chapter 2 by Rodolfo Llimis et a!. describes a new concept related to the dimen­ sions of the calcium action domain at the inner mouth of calcium channels in the squid gi­ ant synapse and its relationship to neurotransmitter release. Chapter 3 by Martin Morad et a!. informs us about new ways of identifying and measuring, by confocal microscopy, in­ dividual sites where calcium release occurs in ventricular myocytes. In the same group Osvaldo Uchitel and Eleonora Katz classify and evaluate the variety of calcium channels at the neuromuscular junction, in Chapter 4. Chapter 5 by Gustavo Brum et a!.

• ATP
• Calcium
• axon
• metabolism
• muscle
• neurotransmitter
• phosphorylation
• protein
• protein synthesis
• skeletal muscle
• synthesis
• tumor

• Instituto de Investigaciones Biológicas Clemente Estable, Montevideo, Uruguay

  J. R. Sotelo, J. C. Benech

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