Cancer Neutron Capture Therapy

Editors: Mishima, Y. (Ed.)

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About this book

There are many human cancers which actively synthesize specific characteristic proteins such as melanomas, thyroid cancer and squamous cell carcinoma. Many cancer researchers have of course tried to utilize this specific activity as a key for the selective treatment of cancers. In the past for example, the molecular hybrid compound of DOPA, a substrate of melanin, and nitrogen mustard N-oxide hydrochloride, a ctyotoxic anti-tumor drug, was synthesized as Melphalan and used to treat malignant melanoma. A major problem arose though in that it was soon found to be highly suppressive toward bone marrow and quite toxic while not being remarkably effective. Thus, malignant melanoma could not be cured by it. Such failure led us to develop a novel bimodal therapeutic system which includes the use of non-toxic potentially cytocidal chemicals which selectively accumulate within the cancer cells and which are converted by a controllable modality into an actively cytocidal element in situ. We can now non-surgically cure malignant melanoma and glioblastoma with our selective cancer treatment, neutron capture therapy (NCT); as can be found in this volume. Included are 124 papers on the latest breaking developments discussed at the Sixth International Symposium on NCT for Cancer held in Kobe during the late autumn of 1994.

Table of contents (126 chapters)

Table of contents (126 chapters)
  • Selective Thermal Neutron Capture Therapy of Cancer Cells Using their Specific Metabolic Activities—Melanoma as Prototype

    Pages 1-26

    Mishima, Yutaka

  • Recent Results with Liposomes as Boron Delivery Vehicles for Boron Neutron Capture Therapy

    Pages 27-36

    Hawthorne, M. Frederick (et al.)

  • Preparation of Epidermal Growth Factor Conjugates Aimed for Boron Neutron Capture Therapy

    Pages 37-42

    Gedda, Lars (et al.)

  • Epidermal Growth Factor (EGF) as a Potential Targeting Agent for Delivery of Boron to Malignant Gliomas

    Pages 43-48

    Capala, Jacek (et al.)

  • Boron Neutron Capture Therapy Against Tumor Cells with Overexpression of the EGF-Receptor

    Pages 49-56

    Carlsson, Jörgen (et al.)

Buy this book

eBook $269.00
price for USA in USD
  • ISBN 978-1-4757-9567-7
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $459.00
price for USA in USD
  • ISBN 978-0-306-45307-6
  • Free shipping for individuals worldwide
  • Institutional customers should get in touch with their account manager
  • Covid-19 shipping restrictions & severe weather in the US may cause delays
  • Usually ready to be dispatched within 3 to 5 business days, if in stock
Softcover $349.99
price for USA in USD
  • ISBN 978-1-4757-9569-1
  • Free shipping for individuals worldwide
  • Institutional customers should get in touch with their account manager
  • Covid-19 shipping restrictions & severe weather in the US may cause delays
  • Usually ready to be dispatched within 3 to 5 business days, if in stock
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Bibliographic Information

Bibliographic Information
Book Title
Cancer Neutron Capture Therapy
Editors
  • Y. Mishima
Copyright
1996
Publisher
Springer US
Copyright Holder
Springer-Verlag US
eBook ISBN
978-1-4757-9567-7
DOI
10.1007/978-1-4757-9567-7
Hardcover ISBN
978-0-306-45307-6
Softcover ISBN
978-1-4757-9569-1
Edition Number
1
Number of Pages
XXVII, 920
Topics