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Advances in Experimental Medicine and Biology

Antiviral Chemotherapy 4

New Directions for Clinical Application and Research

Editors: Mills, John, Volberding, Paul A., Corey, Lawrence (Eds.)

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Hardcover $279.99
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Softcover $219.99
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  • ISBN 978-1-4757-9211-9
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About this book

The three years since our last conference in San Francisco have again seen a dramatic expansion of the number of antivirals either licensed or in the late stages of clinical trials. d4T is now licensed for HIV infection, famciclovir and the oral pro-drug of acyclovir, valacyclovir, are now licensed for VZV infections in some countries. Moreover. oral ganciclovir, cidofovir, and sorivudine are not far behind. Clinical trials with the second-site reverse transcriptase inhibitors and the protease inhibitors for HlV infection are proceeding rapidly and on a broad scale, and the preliminary results would suggest that several of these classes of drugs will be licensed as well. Despite this optimism, however, there is increasing evidence that antiviral-resistant strains of pathogenic viruses will be a significant problem, perhaps especially with therapy of HIV infection, and there remains a desperate need for improved drugs (with either improved efficacy or decreased toxicity, or both) for CMV and HIV infections. This book is the edited proceedings of the Fourth Triennial Conference on Antiviral Chemotherapy, held in San Francisco, in November 1994. The conference was sponsored by the University of California, San Francisco, and co-sponsored by the International Society for Antiviral Research (ISAR), the Macfarlane Burnet Centre for Medical Research in Melbourne, Australia, and the Australian National Centre for HIV Virology Research. The conference had been organized to present an overview of the field of antiviral chemotherapy.

Table of contents (39 chapters)

  • Management of Genital Herpes

    Mertz, Gregory J.

    Pages 1-10

  • Subclinical Shedding of HSV: Its Potential for Reduction by Antiviral Therapy

    Corey, Lawrence (et al.)

    Pages 11-16

  • Famciclovir: Efficacy in Zoster and Issues in the Assessment of Pain

    Boon, Ronald J. (et al.)

    Pages 17-31

  • Valacyclovir HCl (Valtrex™): An Acyclovir Prodrug with Improved Pharmacokinetics and Better Efficacy for Treatment of Zoster

    Smiley, M. Lynn (et al.)

    Pages 33-39

  • Sorivudine: A Potent Inhibitor of Varicella Zoster Virus Replication

    Whitley, Richard J.

    Pages 41-44

Buy this book

eBook $169.00
price for USA in USD (gross)
  • ISBN 978-1-4757-9209-6
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $279.99
price for USA in USD
  • ISBN 978-0-306-45294-9
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $219.99
price for USA in USD
  • ISBN 978-1-4757-9211-9
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Antiviral Chemotherapy 4
Book Subtitle
New Directions for Clinical Application and Research
Editors
  • John Mills
  • Paul A. Volberding
  • Lawrence Corey
Series Title
Advances in Experimental Medicine and Biology
Series Volume
394
Copyright
1996
Publisher
Springer US
Copyright Holder
Springer Science+Business Media New York
eBook ISBN
978-1-4757-9209-6
DOI
10.1007/978-1-4757-9209-6
Hardcover ISBN
978-0-306-45294-9
Softcover ISBN
978-1-4757-9211-9
Series ISSN
0065-2598
Edition Number
1
Number of Pages
XIV, 440
Topics