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Vaccines

New Generation Immunological Adjuvants

  • Book
  • © 1995

Overview

Editors:
  1. Gregory Gregoriadis

    1. School of Pharmacy, University of London, London, England

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  2. Brenda McCormack

    1. School of Pharmacy, University of London, London, England

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  3. Anthony C. Allison

    1. Dawa Corporation, Belmont, USA

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Part of the book series: NATO Science Series A: (NSSA, volume 282)

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Table of contents (18 chapters)

  1. Front Matter

    Pages i-viii
    Download chapter PDF

  2. Adjuvants for New and Improved Vaccines

    • Anthony C. Allison
    Pages 1-14

  3. Liposome Mediated Immunopotentiation and Immunomodulation

    • Nico van Rooijen
    Pages 15-24

  4. Quil A, Anti-Carbohydrate Antibody Specificity and Biological Function

    • H. Snippe, E. Alonso de Velasco, A. F. M. Verheul, J. T. Poolman
    Pages 25-33

  5. Vaccine Adjuvants Based On Gamma Inulin

    • Peter D. Cooper
    Pages 35-44

  6. Interleukin-2 as a Co-Adjuvant for Liposomal Tetanus Toxoid

    • Mayda Gürser, Gregory Gregoriadis
    Pages 45-50

  7. Design of Vaccines for the Induction of Antibody Responses in Th-Cell Deficient Individuals

    • B. Golding, J. Inman, H. Golding
    Pages 51-64

  8. Strategies for the Stimulation of Th Cell Subsets

    • H. Golding, M. B. Zaitseva, C. Lapham, B. Golding
    Pages 65-83

  9. Feline Immunodeficiency Virus as a Vaccine Model

    • M. J. Hosie, O. Jarrett
    Pages 85-95

  10. Rational Design of Vaccine Molecules to Prevent Pertussis

    • M. T. De Magistris, A. >Di Tommaso, M. Pizza, R. Rappuoli
    Pages 97-102

  11. Multicomponent Viral Vaccines and Their Use as Immunogen Delivery Systems

    • Polly Roy
    Pages 103-116

  12. Vaccines Against HPV of the Uterine Cervix: Problems in Clinical Applicability

    • P. Hirnle, W. Erz
    Pages 117-121

  13. Local Chemotherapy of Lymph Node Metastases: Optimization of Targeting Accuracy

    • P. Hirnle, W. Erz
    Pages 123-126

  14. Synthetic Peptide Vaccines: Success at Last

    • R. H. Meloen, J. I. Casal, K. Dalsgaard, J. P. M. Langeveld
    Pages 127-133

  15. Peptide Vaccines; New Approaches to Immunopotentiation

    • M. J. Francis
    Pages 135-140

  16. Genetic Restriction of Responses to Peptide Antigens

    • M. J. Francis
    Pages 141-146

  17. DNA-Based Immunization: Prospects For a Hepatitis B Vaccine

    • Heather L. Davis, Robert G. Whalen
    Pages 147-160

  18. Characterization of Immune Responses Elicited by an Experimental Facilitated-DNA Vaccine for Human Immunodeficiency Virus Type-1 (HIV-1)

    • M. J. Newman, L. Cooney, R. Carrano, J. Boyer, W. V. Williams, B. Wang et al.
    Pages 161-171

  19. Recombinant Self-Replicating RNA Vaccines

    • Peter Liljeström
    Pages 173-180

  20. Back Matter

    Pages 181-192
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Keywords

About this book

During the last decade or so vaccine development has been facilitated by rapid advances in molecular and cell biology. These have laid the foundations of a new generation of vaccines exemplified by subunit vaccines produced through gene cloning and by synthetic peptides mimicking small regions of proteins on the outer coat of viruses. Such peptide~ are capable of eliciting virus-neutralizing antibodies. Unfortunately, subunit and peptide vaccines are only weakly or non immunogenic in the absence of immunological adjuvants that are known to augment specific cell-mediated immune responses to the antigens and to promote the formation of protective antibodies. This book contains the proceedings of the 4th NATO Advanced Studies Institute (ASI) "Vaccines: New Generation Immunological Adjuvants" held at Cape Sounion Beach, Greece, during 24 June -5 . July 1994 and deals in depth with both theoretical and practical aspects of vaccinology. These include the role of antigen presenting cells in the induction of immune responses. immunopotentiation by a variety of new generation immunological adjuvants and vaccine carriers. and recent advances and perspectives in experimental vaccines as well as vaccinatioll with nucleic acids. We express our appreciation to Dr. K. Dalsgaard and Dr. J. L. Virelizier for their cooperatioll in planning the ASI and to Mrs. Concha Pening for her excellent production of the manuscripts. The ASI was held under the sponsorship of NATO Scientific Affairs Division and generously co-sponsored by SmithKline Beecham Pharmaceuticals (Philadelphia).

Editors and Affiliations

  • School of Pharmacy, University of London, London, England

    Gregory Gregoriadis, Brenda McCormack

  • Dawa Corporation, Belmont, USA

    Anthony C. Allison

Bibliographic Information

  • Book Title: Vaccines

  • Book Subtitle: New Generation Immunological Adjuvants

  • Editors: Gregory Gregoriadis, Brenda McCormack, Anthony C. Allison

  • Series Title: NATO Science Series A:

  • DOI: https://doi.org/10.1007/978-1-4613-0357-2

  • Publisher: Springer New York, NY

  • eBook Packages: Springer Book Archive

  • Copyright Information: Plenum Press, New York 1995

  • Hardcover ISBN: 978-0-306-45283-3Published: 29 February 1996

  • Softcover ISBN: 978-1-4613-8014-6Published: 16 September 2011

  • eBook ISBN: 978-1-4613-0357-2Published: 06 December 2012

  • Edition Number: 1

  • Number of Pages: VIII, 192

  • Topics: Immunology, Infectious Diseases, Animal Anatomy / Morphology / Histology, Plant Sciences

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