Advances in Experimental Medicine and Biology

Tissue Renin-Angiotensin Systems

Current Concepts of Local Regulators in Reproductive and Endocrine Organs

Editors: Mukhopadhyay, Amal K., Raizada, Mohan K. (Eds.)

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Recent progress in recombinant DNA technology and the availability of a number of nonpeptide subtype-specific receptor antagonists and of specific antibodies to components of prorenin-renin-angiotensin system (PRAS) have led to rapid advances in the under­ standing of the multifaceted role of angiotensin II, classically known as a peptide hormone of cardiovascular homeostasis. Accumulating evidence sug­ responsible for the regulation gests that, in addition to its role in salt and water metabolism, PRAS may control other physiological functions including neurosecretion, cellular proliferation, hypertrophy and/or differentiation, angiogenesis and gonadal function. At the same time, it is becoming evident that the specialized functions of endocrine glands are not only regulated by trophic hormones but also by locally produced paracrine/autocrine factors. The concept is emerging that tissue PRAS is one such locally active regulatory system. With more and more reproductive and endocrine organs being added to the list of tissues that contain a local tissue PRAS, questions are being raised by the reproductive biologists and endocrinologists as to the role of such systems in the tissues of their interest. On the other hand, the cardiovascular and renovascular physiologists are wondering about the relevance of PRAS in various peripheral tissues compared to those of the classical cardiovascular organs. It appeared, therefore, that the time was ripe for a meeting to consider a merger of interest in these two important but heretofore distinct areas of physiology.

Table of contents (33 chapters)

Table of contents (33 chapters)

Buy this book

eBook $219.00
price for USA in USD
  • ISBN 978-1-4899-0952-7
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $299.00
price for USA in USD
Softcover $279.99
price for USA in USD
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Bibliographic Information

Bibliographic Information
Book Title
Tissue Renin-Angiotensin Systems
Book Subtitle
Current Concepts of Local Regulators in Reproductive and Endocrine Organs
Editors
  • Amal K. Mukhopadhyay
  • Mohan K. Raizada
Series Title
Advances in Experimental Medicine and Biology
Series Volume
377
Copyright
1995
Publisher
Springer US
Copyright Holder
Springer Science+Business Media New York
eBook ISBN
978-1-4899-0952-7
DOI
10.1007/978-1-4899-0952-7
Hardcover ISBN
978-0-306-45077-8
Softcover ISBN
978-1-4899-0954-1
Series ISSN
0065-2598
Edition Number
1
Number of Pages
XI, 458
Topics