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Regulation of Smooth Muscle Contraction

Editors: Moreland, Robert S. (Ed.)

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About this book

Sixth Annual Graduate Hospital Research Symposium REGULATION OF SMOOTH MUSCLE PROGRESS IN SOLVING THE PUZZLE Every so often a scientific conference comes at a time when everyone has new and exciting information, when old "dogmas" do not seem to be as well established, and when speakers and participants alike are ready to challenge interpretations of old and new experimental data. This was such a conference. What turns on a smooth muscle cell? The precise answer to this question has eluded scientists for much longer than I have been involved in the field. We know that an increase in cytosolic calcium is necessary and we know that phosphorylation of the 20 kDa myosin light chain is an important step in the process. We do not know if other processes are necessary for the initiation and lor maintenance of a smooth muscle contraction nor do we know if other processes modulate the regulation of contraction. The goal of the symposium on which this volume is based was to explore the most current hypotheses for the answers to these questions. I believe that after reading the chapters included in this volume, you will agree that this goal was achieved. The importance of calcium and calmodulin dependent myosin light chain phosphoryla­ tion in the regulation of smooth muscle contraction was reinforced by many presentations. However, the status of myosin light chain phosphorylation as a simple calcium dependent switch came under serious suspicion.

Table of contents (47 chapters)

  • Tribute to Professor Edith Bülbring

    Kuriyama, Hirosi

    Pages 1-2

  • Structure-Function Relationships in Smooth Muscle Myosin Light Chain Kinase

    Ito, Masaaki (et al.)

    Pages 3-10

  • Regulation of Smooth Muscle Myosin Light Chain Kinase by Calmodulin

    Means, Anthony R. (et al.)

    Pages 11-24

  • Regulation of Smooth Muscle Actomyosin Function

    Ikebe, Mitsuo (et al.)

    Pages 25-36

  • Biochemical and Functional Characterization of Smooth Muscle Calponin

    Winder, Steven J. (et al.)

    Pages 37-51

Buy this book

eBook $89.00
price for USA in USD (gross)
  • ISBN 978-1-4684-6003-2
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $139.99
price for USA in USD
  • ISBN 978-0-306-44041-0
  • Free shipping for individuals worldwide
  • This title is currently reprinting. You can pre-order your copy now.
Softcover $119.99
price for USA in USD
  • ISBN 978-1-4684-6005-6
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Regulation of Smooth Muscle Contraction
Editors
  • Robert S. Moreland
Copyright
1991
Publisher
Springer US
Copyright Holder
Plenum Press, New York
eBook ISBN
978-1-4684-6003-2
DOI
10.1007/978-1-4684-6003-2
Hardcover ISBN
978-0-306-44041-0
Softcover ISBN
978-1-4684-6005-6
Edition Number
1
Number of Pages
576
Topics