Treatment of Radiation Injuries

1. Front Matter

   Pages i-x

   PDF

2. Hematopoietic Injury Complications

   1. Front Matter

      Pages 1-1

      PDF

   2. Medical Assessment and Therapy in Bone Marrow Failure Due to Radiation Accidents

      • Richard Champlin

      Pages 3-10

   3. Use of rhGM-CSF in Bone Marrow Failure

      • Joseph H. Antin

      Pages 11-18

   4. Blood and Bone Marrow Products in the Treatment of Radiation Injury

      • C. Robert Valeri

      Pages 19-27

   5. Total-Body Irradiation in Bone Marrow Transplantation

      • Rainer Storb, Frederick R. Appelbaum, Friedrich G. Schuening, Robert Raff, Theodore Graham, H. Joachim Deeg

      Pages 29-33

   6. Rescue of Lethally Irradiated Animals

      • Thomas J. MacVittie, Rodney L. Monroy

      Pages 35-49

   7. Myeloprotective Effects of Interleukin-1 Following Exposure to Chemoradiotherapy

      • Joseph Laver, Alfred Gillio, Miguel Abboud, Cristina Gasparetto, David Warren, Richard J. O’Reilly et al.

      Pages 51-60

   8. Effects of Combined Application of IL-3 and G-CSF on Subhuman Primates

      • Dorothee Krumwieh, Ernst Weinmann, Bernhard Siebold, Friedrich R. Seiler

      Pages 61-66

3. Infectious Complications

   1. Front Matter

      Pages 73-73

      PDF

   2. Infections in Radiation Accidents

      • Stephen C. Schimpff

      Pages 75-85

   3. Antibiotics in Postirradiation Infection

      • Itzhak Brook

      Pages 87-93

   4. Treatment of Infectious Complications of the Hematopoietic Syndrome

      • Alexandre B. Oliveira

      Pages 95-100

   5. Role of Immunotherapy in Preventing and Managing Postirradiation Infections

      • Richard I. Walker

      Pages 101-107

   6. Management of Fungal Infections Complicating Granulocytopenia

      • Thomas J. Walsh, Philip A. Pizzo

      Pages 109-113

   7. Prevention of Infection With Endogenous Organisms

      • Gary P. Zaloga

      Pages 115-126

   8. Role of Hematopoietic Growth Factors in Radiation Victims

      • Anna Butturini, Robert Peter Gale

      Pages 127-132

4. Combined Injury Complications

   1. Front Matter

      Pages 139-139

      PDF

   2. The Status of Combined Injuries

      • Erwin F. Hirsch

      Pages 141-144

   3. Combined Radiation and Thermal Injury After Nuclear Attack

      • William K. Becker, Teresa M. Buescher, William G. Cioffi, William F. McManus, Basil A. Pruitt Jr.

      Pages 145-151

The proliferation of radioactive materials in industry, in diagnostic and therapeutic medicine, in scientific and medical research, in the military, and as a source of energy has increased the likelihood of accidental exposure to ionizing radiation. Further, the number of individuals exposed in accidents, such as Chernobyl, U. S. S. R. ; Goiania, Brazil; and San Salvador, El Salvador, underscores the potential for large-scale radiation accidents. Because of these accidents, health care providers have found themselves treating patients with acute radiation injuries and subsequent complications. Often the radiation injuries are combined with burns or other trauma and the infectious and immune complications associated with such injuries. The treatment of victims of these accidents has provided important information about the medical management of radiation casualties. However, development of techniques to improve the diagnosis and treatment of radiation injuries, to collect follow­ up data on survivors, and to determine the long-term effects of uncontrolled radiation exposure must continue. The Armed Forces Radiobiology Research Institute, Bethesda, Maryland, and its Medical Radiobiology Advisory Team sponsored the First Consensus Development Conference on the Treatment of Radiation Injuries in Washington, DC, on May 10-13, 1989. The proceedings of the conference are presented in this volume, which we hope will serve as a reference for clinicians and basic research scientists who require knowledge of the latest developments in the diagnosis and treatment of radiation injuries. This conference was designed specifically to address the areas of hematopoietic injury, infectious complications, and combined injury.

• antibiotics
• assessment
• biology
• care
• diagnosis
• fungal infection
• growth
• health
• health care
• infection
• infections
• infectious
• medicine
• prevention
• therapy

From Book News, Inc.
The May 1989 conference, sponsored by the Armed Forces Radiobiology Research Institute, Bethesda, Maryland, and its Medical Radiobiology Advisory Team, addressed factors related to the hematopoietic injury complications of radiation exposure, the infectious complications resulting from radiation injury, and the current status of combined injury and burn management therapy. A consensus statement provides state-of-the-art guidelines for recognizing and treating radiation injury.
Annotation copyright Book News, Inc. Portland, Or.

• Armed Forces Radiobiology Research Institute, Defense Nuclear Agency, Bethesda, USA

  Doris Browne, Joseph F. Weiss, Thomas J. MacVittie, Madhavan V. Pillai

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