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Electroporation and Electrofusion in Cell Biology

  • Book
  • © 1989

Overview

Editors:
  1. Eberhard Neumann

    1. University of Bielefeld, Bielefeld, FRG

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    You can also search for this editor in PubMed   Google Scholar

  2. Arthur E. Sowers

    1. American Red Cross, Rockville, USA

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    You can also search for this editor in PubMed   Google Scholar

  3. Carol A. Jordan

    1. Science Applications International Corporation, McLean, USA

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Table of contents (27 chapters)

  1. Front Matter

    Pages i-xviii
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  2. Cells in Electric Fields

    1. Front Matter

      Pages 1-1
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    2. Dielectrophoresis and Rotation of Cells

      • H. P. Schwan
      Pages 3-21

    3. Cellular Spin Resonance

      • Ingolf Lamprecht, Maja Mischel
      Pages 23-35

    4. Dielectrophoresis

      • Francisco J. Iglesias, Carlos Santamaría, M. Carmen López, Angel Domínguez
      Pages 37-57

  3. Electroporation

    1. Front Matter

      Pages 59-59
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    2. The Relaxation Hysteresis of Membrane Electroporation

      • Eberhard Neumann
      Pages 61-82

    3. Electrical Breakdown of Lipid Bilayer Membranes

      • Leonid V. Chernomordik, Yuri A. Chizmadzhev
      Pages 83-95

    4. Stochastic Model of Electric Field-Induced Membrane Pores

      • Istvan P. Sugar
      Pages 97-110

    5. Theory of Electroporation

      • James C. Weaver, Kevin T. Powell
      Pages 111-126

    6. Leaks Induced by Electrical Breakdown in the Erythrocyte Membrane

      • Bernhard Deuticke, Karl Schwister
      Pages 127-148

    7. Electroporation of Cell Membranes

      • Tian Yow Tsong
      Pages 149-163

  4. Electrofusion

    1. Front Matter

      Pages 165-165
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    2. Electrofusion Kinetics

      • David A. Stenger, Sek Wen Hui
      Pages 167-180

    3. Electrofusion of Lipid Bilayers

      • Grigory B. Melikyan, Leonid V. Chernomordik
      Pages 181-192

    4. Role of Proteases in Electrofusion of Mammalian Cells

      • Takako Ohno-Shosaku, Yasunobu Okada
      Pages 193-202

    5. Electrofusion of Mammalian Cells and Giant Unilamellar Vesicles

      • J. Teissié, M. P. Rols, C. Blangero
      Pages 203-214

    6. Cell Fusion and Cell Poration by Pulsed Radio-Frequency Electric Fields

      • Donald C. Chang
      Pages 215-227

    7. The Mechanism of Electroporation and Electrofusion in Erythrocyte Membranes

      • Arthur E. Sowers
      Pages 229-256

  5. Applications

    1. Front Matter

      Pages 257-257
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Keywords

About this book

Cells can be funny. Try to grow them with a slightly wrong recipe, and they turn over and die. But hit them with an electric field strong enough to knock over a horse, and they do enough things to justify international meetings, to fill a sizable book, and to lead one to speak of an entirely new technology for cell manipulation. The very improbability of these events not only raises questions about why things happen but also leads to a long list of practical systems in which the application of strong electric fields might enable the merger of cell contents or the introduction of alien but vital material. Inevitably, the basic questions and the practical applications will not keep in step. The questions are intrinsically tough. It is hard enough to analyze the action of the relatively weak fields that rotate or align cells, but it is nearly impossible to predict responses to the cell-shredding bursts of electricity that cause them to fuse or to open up to very large molecular assemblies. Even so, theoretical studies and systematic examination of model systems have produced some creditable results, ideas which should ultimately provide hints of what to try next.

Editors and Affiliations

  • University of Bielefeld, Bielefeld, FRG

    Eberhard Neumann

  • American Red Cross, Rockville, USA

    Arthur E. Sowers

  • Science Applications International Corporation, McLean, USA

    Carol A. Jordan

Bibliographic Information

  • Book Title: Electroporation and Electrofusion in Cell Biology

  • Editors: Eberhard Neumann, Arthur E. Sowers, Carol A. Jordan

  • DOI: https://doi.org/10.1007/978-1-4899-2528-2

  • Publisher: Springer New York, NY

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer Science+Business Media New York 1989

  • Hardcover ISBN: 978-0-306-43043-5Published: 31 May 1989

  • Softcover ISBN: 978-1-4899-2530-5Published: 15 July 2013

  • eBook ISBN: 978-1-4899-2528-2Published: 11 November 2013

  • Edition Number: 1

  • Number of Pages: XVIII, 436

  • Topics: Biochemistry, general, Biotechnology, Animal Anatomy / Morphology / Histology, Plant Sciences

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