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Advances in Experimental Medicine and Biology

The Molecular Immunology of Complex Carbohydrates

Authors: Wu, Albert M., Adams, L. Garry

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About this book

During the past three decades, the sugar moiety of complex carbohydrates has been found to be involved in important interactions of immunological specificity of antigens and to participate in a variety of cellular functions. The long polysaccharide side chains of the lipopolysaccharides on the outer membrane of Gram negative organisms provide surface antigens for differential serodiagnosis. Bacterial surface lectins are important in mediating the attachment of bacteria to host cells in the of infectious diseases. The carbohydrate pathogenesis moieties of cell surface glycoconjugates (glycoproteins and glycolipids) of mammals are the sites for intercellular recognition and for the regulatory molecular interactions such as interaction of complex carbohydrate with hormones or hepatic lectins. The carbohydrate side chains of many complex carbohydrates play essential roles as antigenic determinants b of human blood group ABH, Lea, Le , I, and i activities, as the Forssman specific determinant, and as tumor associated antigenic determinants. Prompted by these and other advances in the field, a Symposium on Molecular Immunology of Complex Carbohydrates was organized as a satellite meeting of the 8th International Glycoconjugate Conference held on September 8- 13, 1985, in Houston, Texas, U. S . A. Many eminent scientists contributed their knowledge at this meeting. The lecture and poster materials of the symposium are contained in this proceeding book, which is divided into four Sections and one Appendix. Section I is entitled Antibody Specificity, Epitope, and Lectinology. Dr. Elvin A.

Table of contents (37 chapters)

Table of contents (37 chapters)
  • Antibody Combining Sites: How Much of the Antibody Repertoire are we Seeing? How does it Influence Our Understanding of the Structural and Genetic Basis of Antibody Complimentarity?

    Pages 1-45

    Kabat, Elvin A.

  • Sialic Acids as Antigenic Determinants of Complex Carbohydrates

    Pages 47-72

    Schauer, Roland

  • Blood Group Active Haptens in Urine and Faeces

    Pages 73-81

    Lundblad, Arne (et al.)

  • The Separation of Immunocyte Subpopulations by Use of Various Lectins

    Pages 83-104

    Osawa, Toshiaki

  • Mannose-Binding Proteins of Animal Origin

    Pages 105-121

    Lee, Y. C.

Buy this book

eBook $89.00
price for USA in USD
  • ISBN 978-1-4613-1663-3
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $139.99
price for USA in USD
  • ISBN 978-0-306-42818-0
  • Free shipping for individuals worldwide
  • Immediate ebook access, if available*, with your print order
  • Usually ready to be dispatched within 3 to 5 business days.
Softcover $119.99
price for USA in USD
  • ISBN 978-1-4612-8923-4
  • Free shipping for individuals worldwide
  • Immediate ebook access, if available*, with your print order
  • Usually ready to be dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
The Molecular Immunology of Complex Carbohydrates
Authors
Series Title
Advances in Experimental Medicine and Biology
Series Volume
228
Copyright
1988
Publisher
Springer US
Copyright Holder
Plenum Press, New York
eBook ISBN
978-1-4613-1663-3
DOI
10.1007/978-1-4613-1663-3
Hardcover ISBN
978-0-306-42818-0
Softcover ISBN
978-1-4612-8923-4
Series ISSN
0065-2598
Edition Number
1
Number of Pages
XIV, 868
Topics

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