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Electrochemical Sensors in Immunological Analysis

  • Book
  • © 1987

Overview

Editors:
  1. T. T. Ngo

    1. University of California, Irvine, Irvine, USA

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Table of contents (25 chapters)

  1. Front Matter

    Pages i-xi
    Download chapter PDF

  2. On the Direct Immunochemical Potentiometric Signal

    • Michael Thompson, Joseph S. Tauskela, Ulrich J. Krull
    Pages 1-18

  3. Selective Antibody Responsive Membrane Electrodes

    • M. Y. Keating
    Pages 19-34

  4. Electroimmunoassay of PGE2: An Antibody-Sensitive Electrode Based Competitive Protein-Binding Assay

    • George R. Connell, Kenton M. Sanders
    Pages 35-45

  5. Immuno-Potentiometric Sensors with Antigen Coated Membrane

    • Shuichi Suzuki, Masuo Aizawa
    Pages 47-59

  6. The Opsonized Electrode

    • H. Allen O. Hill, Nicholas J. Walton
    Pages 61-75

  7. Homogeneous Voltammetric Immunoassay of Haptens

    • Sam A. McClintock, William C. Purdy
    Pages 77-85

  8. Immunoassay by Differential Pulse Polarography and Anodic Stripping Voltammetry

    • Matthew J. Doyle, Kenneth R. Wehmeyer, William R. Heineman, H. Brian Halsall
    Pages 87-102

  9. Separation-Free (Homogeneous) Amperometric Immunoassay Using an Apoenzyme as the Label

    • That T. Ngo
    Pages 103-115

  10. Digoxin Homogeneous Enzyme Immunoassay with Amperometric Detection

    • D. Scott Wright, H. Brian Halsall, William R. Heineman
    Pages 117-130

  11. Antibody to an Enzyme as the Modulator in Separation-Free Enzyme Immunoassays with Electrochemical Sensor

    • T. T. Ngo
    Pages 131-143

  12. Immunochemical Determination of Creatine Kinase Isoenzyme-MB

    • Shia S. Kuan, George G. Guilbault
    Pages 145-165

  13. Immunosensor Based on Labeled Liposome Entrapped-Enzymes

    • Makoto Haga
    Pages 167-177

  14. Measurement of Complement Fixation with Ion Selective Membrane Electrodes

    • Paul D’Orazio
    Pages 179-194

  15. Antibody-Antigen Precipitin Reaction Monitoring with an Ion Selective Electrode

    • Peter W. Alexander
    Pages 195-202

  16. Enzyme-Linked Immunoassay with a Fluoride Ion Selective Electrode

    • Peter W. Alexander
    Pages 203-210

  17. Heterogeneous Potentiometric Enzyme Immunoassay for Antigens and Haptens with Iodide Selective Electrode

    • Jean-Louis Boitieux, Gerard Desmet, Daniel Thomas
    Pages 211-237

  18. Enzyme Immunoassay Using the Ammonia Gas-Sensing Electrode

    • Carl R. Gebauer
    Pages 239-255

  19. Homogeneous and Heterogeneous Enzyme Immunoassays Monitored with Carbon Dioxide Sensing Membrane Electrodes

    • C. A. Broyles, G. A. Rechnitz
    Pages 257-268

  20. Enzyme-Linked Immunosorbent Assays Using Oxygen-Sensing Electrode

    • Masuo Aizawa
    Pages 269-278
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Keywords

About this book

The development of radioimmunoassay (RIA) by R.S. Yalow and S.A. Berson in 1959 opens up a new avenue in ultra­ sensitive analysis of trace substances in complex biological systems. In recognition of the enormous contributions of RIA to basic research in biology and to routine clinical tests in laboratory medicine, R.S. Yalow, the co-developer of RIA, was awarded, in 1977, the Nobel Prize for Medicine and Physiology. The basic principle of RIA is elegantly simple. It is based on a specific, competitive binding reaction between the analyte and the radio-labeled analog of the analyte for the specific antibody raised to the analyte. The combination of high specificity and affinity of an antibody molecule makes it a very versatile analytical reagent capable of reacting specifically with analytes at a very low concentration in a complex solution such as serum. The sensitivity of RIA is provided by using a radioactive tracer.

Editors and Affiliations

  • University of California, Irvine, Irvine, USA

    T. T. Ngo

Bibliographic Information

  • Book Title: Electrochemical Sensors in Immunological Analysis

  • Editors: T. T. Ngo

  • DOI: https://doi.org/10.1007/978-1-4899-1974-8

  • Publisher: Springer New York, NY

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer Science+Business Media New York 1987

  • Hardcover ISBN: 978-0-306-42580-6Published: 31 August 1987

  • Softcover ISBN: 978-1-4899-1976-2Published: 12 June 2013

  • eBook ISBN: 978-1-4899-1974-8Published: 11 November 2013

  • Edition Number: 1

  • Number of Pages: XII, 348

  • Topics: Immunology, Biochemistry, general, Biotechnology

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