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Electrochemical Sensors in Immunological Analysis

Editors: Ngo, That T. (Ed.)

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eBook $139.00
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  • ISBN 978-1-4899-1974-8
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Hardcover $229.99
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Softcover $179.99
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  • ISBN 978-1-4899-1976-2
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About this book

The development of radioimmunoassay (RIA) by R.S. Yalow and S.A. Berson in 1959 opens up a new avenue in ultra­ sensitive analysis of trace substances in complex biological systems. In recognition of the enormous contributions of RIA to basic research in biology and to routine clinical tests in laboratory medicine, R.S. Yalow, the co-developer of RIA, was awarded, in 1977, the Nobel Prize for Medicine and Physiology. The basic principle of RIA is elegantly simple. It is based on a specific, competitive binding reaction between the analyte and the radio-labeled analog of the analyte for the specific antibody raised to the analyte. The combination of high specificity and affinity of an antibody molecule makes it a very versatile analytical reagent capable of reacting specifically with analytes at a very low concentration in a complex solution such as serum. The sensitivity of RIA is provided by using a radioactive tracer.

Table of contents (25 chapters)

  • On the Direct Immunochemical Potentiometric Signal

    Thompson, Michael (et al.)

    Pages 1-18

  • Selective Antibody Responsive Membrane Electrodes

    Keating, M. Y.

    Pages 19-34

  • Electroimmunoassay of PGE2: An Antibody-Sensitive Electrode Based Competitive Protein-Binding Assay

    Connell, George R. (et al.)

    Pages 35-45

  • Immuno-Potentiometric Sensors with Antigen Coated Membrane

    Suzuki, Shuichi (et al.)

    Pages 47-59

  • The Opsonized Electrode

    Hill, H. Allen O. (et al.)

    Pages 61-75

Buy this book

eBook $139.00
price for USA in USD (gross)
  • ISBN 978-1-4899-1974-8
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $229.99
price for USA in USD
  • ISBN 978-0-306-42580-6
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $179.99
price for USA in USD
  • ISBN 978-1-4899-1976-2
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Electrochemical Sensors in Immunological Analysis
Editors
  • That T. Ngo
Copyright
1987
Publisher
Springer US
Copyright Holder
Springer Science+Business Media New York
eBook ISBN
978-1-4899-1974-8
DOI
10.1007/978-1-4899-1974-8
Hardcover ISBN
978-0-306-42580-6
Softcover ISBN
978-1-4899-1976-2
Edition Number
1
Number of Pages
XII, 348
Topics